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CCR2: C-C motif chemokine receptor 2

1 protein, 201 patents, 10 drugs, 36 trials, 9,046 NIH grants and 15,462 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCCR2HGNC
NameC-C motif chemokine receptor 2HGNC
NCBI Gene ID729230NCBI Gene
HGNC IDHGNC:1603HGNC
EnsemblENSG00000121807NCBI Gene
AliasesCC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, FLJ78302, MCP-1-R, PCLUDNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P41597C-C chemokine receptor type 23747Ensembl, GeneID, HGNCUniProt

Patents 201

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026185124 A12026-09-10286P41597Espacenet
WO 2026185128 A12026-09-10286P41597Espacenet
WO 2026170016 A12026-08-139P41597Espacenet
EP 4724076 A22026-04-1569P41597Espacenet
JP 2026062654 A2026-04-1023P41597Espacenet
JP 2026510989 A2026-04-1018P41597Espacenet
EP 4705273 A22026-03-11362P41597Espacenet
EP 4705273 A22026-03-11446P41597Espacenet
JP 2026004568 A2026-01-1441040P41597Espacenet
JP 2026004568 A2026-01-1441041P41597Espacenet

Drugs 10

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AZD2423CHEMBL3545221C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
BMS-741672CHEMBL4457723C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
BMS-813160CHEMBL4594419C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
CENICRIVIROCCHEMBL2110727C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
ILACIRNONCHEMBL2178573C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
JNJ-41443532CHEMBL2204263C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
MK-0812CHEMBL3305901C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
PF-04634817CHEMBL5095029C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
PF-4136309CHEMBL2029422C-C chemokine receptor type 2 antagonistANTAGONISTChEMBL
PLOZALIZUMABCHEMBL3707228C-C chemokine receptor type 2 inhibitorINHIBITORChEMBL

Trials 36

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04593940CENICRIVIROCPHASE32023-04-21ClinicalTrials.gov
NCT04500418CENICRIVIROCPHASE2ClinicalTrials.gov
NCT04488081CENICRIVIROCPHASE2ClinicalTrials.gov
NCT04123379BMS-813160PHASE2ClinicalTrials.gov
NCT03703908ILACIRNONPHASE22024-02-06ClinicalTrials.gov
NCT03536754ILACIRNONPHASE22023-12-05ClinicalTrials.gov
NCT03517540CENICRIVIROCPHASE22021-11-12ClinicalTrials.gov
NCT03496662BMS-813160PHASE1/PHASE22022-11-30ClinicalTrials.gov
NCT03184870BMS-813160PHASE1/PHASE22025-10-09ClinicalTrials.gov
NCT03059446CENICRIVIROCPHASE22022-02-02ClinicalTrials.gov

NIH grants 9046

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant452,025NIH's project files
P30CA016672Cancer Center Support Grant372,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award262,025NIH's project files
P51OD011104Tulane National Primate Research Center202,025NIH's project files
P30CA091842Cancer Center Support Grant192,025NIH's project files
P30CA013330Cancer Center Support Grant172,025NIH's project files
P51OD011132Emory National Primate Research Center162,025NIH's project files
R01HL076246Chemokines in healing myocardial infarction162,025NIH's project files
R01HL085440Resolution of inflammation in healing myocardial infarcts162,025NIH's project files
R35HL145212Targeted Molecular Probes for Atherosclerosis Imaging and Therapy162,025NIH's project files

Papers 15462

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823874PubTator, text miningPubMed
42805351PubTator, text miningPubMed
42801717PubTator, text miningPubMed
42787504PubTator, text miningPubMed
42783079PubTator, text miningPubMed
42769527PubTator, text miningPubMed
42769463PubTator, text miningPubMed
42769001PubTator, text miningPubMed
42768407PubTator, text miningPubMed
42762963PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license