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Gene · 729238

SFTPA2: surfactant protein A2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SFTPA2: surfactant protein A2. Genes, record 729238. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/729238

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Gene

Symbol
SFTPA2
HGNC
Name
surfactant protein A2
HGNC
NCBI Gene ID
729238
NCBI Gene
HGNC ID
HGNC:10799
HGNC
Ensembl
ENSG00000185303
NCBI Gene
Aliases
COLEC5, ILD2, PSAP, PSP-A, PSPA, SFTP1, SFTPA2B, SP-2A, SP-A, SP-A2, SPA2, SPAII
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8IWL1Pulmonary surfactant-associated protein A22480Ensembl, GeneID, HGNC

Source UniProt

Patents52

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026027383 A2026-02-1836Q8IWL1Espacenet
JP 2026004568 A2026-01-1465903Q8IWL1Espacenet
JP 2026004568 A2026-01-1465904Q8IWL1Espacenet
EP 4650780 A22025-11-199088Q8IWL1Espacenet
JP 2025147176 A2025-10-0612171Q8IWL1Espacenet
JP 2025147176 A2025-10-0612172Q8IWL1Espacenet
JP 2025517970 A2025-06-129088Q8IWL1Espacenet
JP 2025028160 A2025-02-2812171Q8IWL1Espacenet
JP 2025028160 A2025-02-2812172Q8IWL1Espacenet
JP 2025023922 A2025-02-192Q8IWL1Espacenet

1 to 10 of 52

See all 52 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,206

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSFTPA2 papersNewest fiscal year
U19AI125357Innate Immunity and Viral Infection in Asthma92025
R01AI052474Vaccine Assembly from Surface Proteins of Staphylococcus aureus82025
R01HL095993Derivation of lung epithelia from iPS cells for advanced disease modeling82025
P30ES006694Southwest Environmental Health Sciences Center62025
P30DK054759Precision Medicine Center for Cystic Fibrosis52025
R01HL135062Mechanisms of Telomere-Mediated Lung Disease52025
P30ES013508Center of Excellence in Environmental Toxicology42025
T32HL094296Interdisciplinary Training Program in Lung Research42025
UL1TR001863Yale Clinical and Translational Science Award42025
ZIAAI000904Staphylococcal pathogenesis42025

1 to 10 of 1,206Source NIH's project files

See all 1,206 nih grants

Papers2,065

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Split aptamer-regulated AuNF nanozymes for colorimetric and electrochemical dual-readout kanamycin biosensing.Talanta202742580248PubTator, text miningPubMed
The phage shock protein A (PspA) maintains membrane potential and supports NADH dehydrogenase function in mycobacteria.bioRxiv202642818691PubTator, text miningPubMed
Plasma Biomarkers of Acute Respiratory Distress Syndrome Vary with Body Size in the Absence of Acute Illness.medRxiv202642818161PubTator, text miningPubMed
Next-Generation Sequencing in Pulmonary Fibrosis: Translational Promise and Current Clinical Limitations.Curr Issues Mol Biol202642510961PubTator, text miningPubMed
A Novel SFTPA2 Variant in a Child with Surfactant Dysfunction-Associated Interstitial Lung Disease.Indian J Pediatr202642384259PubTator, text miningPubMed
A pan-serotype human monoclonal antibody protects against pneumococcal infection by targeting multiple choline binding domain proteins.bioRxiv202642282568PubTator, text miningPubMed
Label-free electrochemical split-aptamer aptasensor with signal amplification via flower-like gold nanostructures for ultrasensitive detection of kanamycin in water.Talanta202642172966PubTator, text miningPubMed
Membrane interaction of cyanobacterial and chloroplast ESCRT-III proteins.Plant J202641937622PubTator, text miningPubMed
Rapid but Transient Microevolution with Minimal Recombination During High-Transmission Streptococcus pneumoniae Carriage in a Day-Care Cohort.Microb Drug Resist202641925144PubTator, text miningPubMed
Targeting the epithelium in pulmonary fibrosis.Eur Respir Rev202641881452PubTator, text miningPubMed

1 to 10 of 2,065

See all 2,065 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/729238

GET https://conductscience.org/api/genes/v1/729238/patents?page=2