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TXK: TXK tyrosine kinase

1 protein, 44 patents, 2 drugs, 24 trials, 20,330 NIH grants and 81,285 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTXKHGNC
NameTXK tyrosine kinaseHGNC
NCBI Gene ID7294NCBI Gene
HGNC IDHGNC:12434HGNC
EnsemblENSG00000074966NCBI Gene
AliasesBTKL, PSCTK5, PTK4, RLK, TKLNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P42681Tyrosine-protein kinase TXK5271Ensembl, GeneID, HGNCUniProt

Patents 44

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468764P42681Espacenet
EP 4641201 A22025-10-291900P42681Espacenet
JP 2025517969 A2025-06-121900P42681Espacenet
US 11446398 B22022-09-2094210P42681Espacenet
US 11351168 B12022-06-076P42681Espacenet
JP 2022524081 A2022-04-27197181P42681Espacenet
KR 1020210128370 A2021-10-2645P42681Espacenet
KR 1020210125457 A2021-10-1822P42681Espacenet
US 11078247 B22021-08-0312184P42681Espacenet
US 10828300 B22020-11-106P42681Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RITLECITINIBCHEMBL4085457TEC family kinase inhibitorINHIBITORChEMBL
RITLECITINIB TOSYLATECHEMBL5314649TEC family kinase inhibitorINHIBITORChEMBL

Trials 24

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07228390RITLECITINIBPHASE2ClinicalTrials.gov
NCT07226531RITLECITINIBClinicalTrials.gov
NCT07200128RITLECITINIBClinicalTrials.gov
NCT07152626RITLECITINIBPHASE2ClinicalTrials.gov
NCT07152119RITLECITINIB TOSYLATEClinicalTrials.gov
NCT07029828RITLECITINIBPHASE3ClinicalTrials.gov
NCT07029711RITLECITINIBPHASE3ClinicalTrials.gov
NCT06873945RITLECITINIBPHASE3ClinicalTrials.gov
NCT06573593RITLECITINIBClinicalTrials.gov
NCT06531109RITLECITINIBClinicalTrials.gov

NIH grants 20330

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant9392,025NIH's project files
P30CA008748Cancer Center Support Grant7882,025NIH's project files
P30CA006973Regional Oncology Research Center1832,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)1542,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant1332,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant1312,025NIH's project files
P30CA068485Cancer Center Support Grant1112,025NIH's project files
P30CA016058Cancer Center Support Grant1032,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant862,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase792,025NIH's project files

Papers 81285

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826440PubTator, text miningPubMed
42824263PubTator, text miningPubMed
42823576PubTator, text miningPubMed
42822865PubTator, text miningPubMed
42820177PubTator, text miningPubMed
42819702PubTator, text miningPubMed
42818944PubTator, text miningPubMed
42818285PubTator, text miningPubMed
42814119PubTator, text miningPubMed
42813644PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license