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ACOD1: aconitate decarboxylase 1
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Gene · 730249

Papers2,030

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 2,030

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TitleJournalYearPMIDFound bySource
Hypoxia Remodels the Extracellular Vesicle Proteome to Drive Metastasis in Breast Cancer via Metabolic-Epigenetic Coupling.J Proteome Res202642341239PubTator, text miningPubMed
De novo pyrimidine synthesis controls germinal center B cell and plasma cell fates and systemic autoimmunity.Cell Rep202642334921PubTator, text miningPubMed
Arginine metabolism supports de novo pyrimidine biosynthesis to block DNA damage and maintain Epstein-Barr virus latency.mBio202642294882PubTator, text miningPubMed
Lessons from the slide preparation: A new species of Kaluginia (Diptera, Chironomidae) from China.Zookeys202642291624PubTator, text miningPubMed
Identification of a metabolic-immune crosstalk in Still's disease: monocyte/macrophage-derived immunometabolite itaconate dictates hepatic immunopathology via the CXCL10-CD8 T cell axis.Exp Mol Med202642249091PubTator, text miningPubMed
IRG1/itaconate rewires macrophage and lung tumor metabolism through G6PD inhibition.Cell Metab202642235511PubTator, text miningPubMed
Xijiao Dihuang decoction ameliorates sepsis by regulating macrophage polarization via activation of the itaconate-mediated Nrf2/HO-1 pathway.J Ethnopharmacol202642202917PubTator, text miningPubMed
Metabolite-neuro-immune relay in chronic pain: spatial-temporal lactate, succinate and itaconate signalling as drivers of glial reprogramming and neuronal sensitisation.Front Pharmacol202642131819PubTator, text miningPubMed
Not all Group B Streptococci are alike: macrophage responses reveal inflammatory and immune-evasive strains.Front Cell Infect Microbiol202642079743PubTator, text miningPubMed
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice.Nat Metab202642056505PubTator, text miningPubMed
Itaconate modifications: Mechanisms and applications.J Intensive Med202642028144PubTator, text miningPubMed
[Mechanism Study of Aconitase 1 Promoting Hepatocellular Carcinoma Growth via the Itaconic Acid-Autophagy Axis].Sichuan Da Xue Xue Bao Yi Xue Ban202642021887PubTator, text miningPubMed
Lactate-driven pyrimidine synthesis promotes ferroptosis resistance in hepatocellular carcinoma.Mol Biomed202641996004PubTator, text miningPubMed
PFKFB3 activates CAD to enhance de novo pyrimidine synthesis for cell growth.Cell Rep202641989915PubTator, text miningPubMed
Human pneumovirus induces IFN-dependent expression of the immune-responsive gene 1 and is inhibited by 4-octyl itaconate in human macrophages.NAR Mol Med202641969424PubTator, text miningPubMed
Oncolytic virus hijacks GOT1 and pyrimidinosomes to fuel pyrimidine synthesis for replication in tumor cells.Tumour Virus Res202641966328PubTator, text miningPubMed
iNOS modulates inflammatory responses in an NO-independent manner through direct interaction with IRG1 in mitochondria.Nat Metab202641963607PubTator, text miningPubMed
Mitochondrial iNOS blocks itaconate production by interacting with IRG1.Nat Metab202641963606PubTator, text miningPubMed
Itaconate as a Potent Regulator of Neutrophil Responses in Host Defence and Inflammation.Scand J Immunol202641919324PubTator, text miningPubMed
ACOD1 regulates microglial arginine metabolism and inflammatory responses.Front Immunol202641918748PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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