ConductScience.org, home

Gene · 7307

U2AF1: U2 small nuclear RNA auxiliary factor 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. U2AF1: U2 small nuclear RNA auxiliary factor 1. Genes, record 7307. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7307

On this page

Gene

Symbol
U2AF1
HGNC
Name
U2 small nuclear RNA auxiliary factor 1
HGNC
NCBI Gene ID
7307
NCBI Gene
HGNC ID
HGNC:12453
HGNC
Ensembl
ENSG00000160201
NCBI Gene
Aliases
FP793, RN, RNU2AF1, U2AF35, U2AFBP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01081Splicing factor U2AF 35 kDa subunit2401Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468839Q01081Espacenet
EP 4650780 A22025-11-1918923Q01081Espacenet
EP 4650780 A22025-11-193466Q01081Espacenet
EP 4641201 A22025-10-293053Q01081Espacenet
JP 2025517969 A2025-06-123053Q01081Espacenet
JP 2025517970 A2025-06-123466Q01081Espacenet
JP 2025517970 A2025-06-1218923Q01081Espacenet
JP 2025032204 A2025-03-1137927Q01081Espacenet
EP 4461818 A22024-11-1337927Q01081Espacenet
JP 2023058610 A2023-04-2537927Q01081Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,879

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleU2AF1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant772025
P30CA016672Cancer Center Support Grant522025
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia272025
P50CA171963Specialized Program of Research Excellence (SPORE) in Leukemia232025
P30CA016058Cancer Center Support Grant182025
P30CA091842Cancer Center Support Grant162025
P30CA015704Cancer Center Support Grant152025
R01GM070503Molecular Recognition During Pre-mRNA Splicing152025
P30CA076292Moffitt Cancer Center Support Grant132025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias112025

1 to 10 of 1,879Source NIH's project files

See all 1,879 nih grants

Papers3,382

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Concurrent RUNX1::MECOM and RUNX1::PRDM16 Fusions from a Novel Genomic Breakpoint: First Report of a Dual-Fusion Mechanism in Acute Myeloid Leukemia.Onco Targets Ther202642764945PubTator, text miningPubMed
Serial VAF Kinetics Reveal Dynamic Clonal Evolution Associated With Progression in Clonal Cytopenia of Undetermined Significance.Eur J Haematol202642728663PubTator, text miningPubMed
Genome-wide CRISPR screens map synthetic lethal interactions across recurrent cancer driver alterations.Cell Rep202642726641PubTator, text miningPubMed
Targeting splicing-derived neoantigens for precision cancer immunotherapy.Front Immunol202642724627PubTator, text miningPubMed
The DNA/RNA Helicase SETX Maintains R-Loop Homeostasis to Promote Chemoresistance in Ovarian Cancer.Cancer Sci202642713672PubTator, text miningPubMed
Splicing modulation as an emerging therapeutic strategy in cancer: molecular mechanisms, clinical development, and future perspectives.Jpn J Clin Oncol202642704825PubTator, text miningPubMed
Distinct clinical and genetic characteristics of myelodysplastic syndrome in younger patients.Br J Haematol202642630001PubTator, text miningPubMed
Pervasive noise in human pre-mRNA splice site selection.Mol Cell202642607686PubTator, text miningPubMed
Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas.iScience202642602702PubTator, text miningPubMed
Acute Myeloid Leukemia with Myelodysplasia-Related Gene Mutations.J Clin Med202642590061PubTator, text miningPubMed

1 to 10 of 3,382

See all 3,382 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7307

GET https://conductscience.org/api/genes/v1/7307/patents?page=2