Gene · 7307
U2AF1: U2 small nuclear RNA auxiliary factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. U2AF1: U2 small nuclear RNA auxiliary factor 1. Genes, record 7307. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7307
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q01081 | Splicing factor U2AF 35 kDa subunit | 240 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 68839 | Q01081 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 18923 | Q01081 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3466 | Q01081 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3053 | Q01081 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3053 | Q01081 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3466 | Q01081 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 18923 | Q01081 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 37927 | Q01081 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 37927 | Q01081 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 37927 | Q01081 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,879
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | U2AF1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 77 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 52 | 2025 |
| R01HL128239 | Genetic and molecular basis for SRSF2 mutations in myelodysplasia | 27 | 2025 |
| P50CA171963 | Specialized Program of Research Excellence (SPORE) in Leukemia | 23 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 18 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 16 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 15 | 2025 |
| R01GM070503 | Molecular Recognition During Pre-mRNA Splicing | 15 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 13 | 2025 |
| P01CA066996 | Development of Novel Therapeutic Strategies in Human Leukemias | 11 | 2025 |
1 to 10 of 1,879Source NIH's project files
See all 1,879 nih grantsPapers3,382
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Concurrent RUNX1::MECOM and RUNX1::PRDM16 Fusions from a Novel Genomic Breakpoint: First Report of a Dual-Fusion Mechanism in Acute Myeloid Leukemia. | Onco Targets Ther | 2026 | 42764945 | PubTator, text mining | PubMed |
| Serial VAF Kinetics Reveal Dynamic Clonal Evolution Associated With Progression in Clonal Cytopenia of Undetermined Significance. | Eur J Haematol | 2026 | 42728663 | PubTator, text mining | PubMed |
| Genome-wide CRISPR screens map synthetic lethal interactions across recurrent cancer driver alterations. | Cell Rep | 2026 | 42726641 | PubTator, text mining | PubMed |
| Targeting splicing-derived neoantigens for precision cancer immunotherapy. | Front Immunol | 2026 | 42724627 | PubTator, text mining | PubMed |
| The DNA/RNA Helicase SETX Maintains R-Loop Homeostasis to Promote Chemoresistance in Ovarian Cancer. | Cancer Sci | 2026 | 42713672 | PubTator, text mining | PubMed |
| Splicing modulation as an emerging therapeutic strategy in cancer: molecular mechanisms, clinical development, and future perspectives. | Jpn J Clin Oncol | 2026 | 42704825 | PubTator, text mining | PubMed |
| Distinct clinical and genetic characteristics of myelodysplastic syndrome in younger patients. | Br J Haematol | 2026 | 42630001 | PubTator, text mining | PubMed |
| Pervasive noise in human pre-mRNA splice site selection. | Mol Cell | 2026 | 42607686 | PubTator, text mining | PubMed |
| Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas. | iScience | 2026 | 42602702 | PubTator, text mining | PubMed |
| Acute Myeloid Leukemia with Myelodysplasia-Related Gene Mutations. | J Clin Med | 2026 | 42590061 | PubTator, text mining | PubMed |
1 to 10 of 3,382
See all 3,382 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7307
GET https://conductscience.org/api/genes/v1/7307/patents?page=2