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Gene · 7318

UBA7: ubiquitin like modifier activating enzyme 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UBA7: ubiquitin like modifier activating enzyme 7. Genes, record 7318. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7318

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Gene

Symbol
UBA7
HGNC
Name
ubiquitin like modifier activating enzyme 7
HGNC
NCBI Gene ID
7318
NCBI Gene
HGNC ID
HGNC:12471
HGNC
Ensembl
ENSG00000182179
NCBI Gene
Aliases
D8, UBA1B, UBE1L, UBE2, UBE7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P41226Ubiquitin-like modifier-activating enzyme 71,0126Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-196012P41226Espacenet
JP 2025529142 A2025-09-045146P41226Espacenet
US 12371689 B22025-07-295146P41226Espacenet
JP 2025517970 A2025-06-126012P41226Espacenet
US 11564998 B22023-01-315575P41226Espacenet
US 11446398 B22022-09-2095354P41226Espacenet
JP 2022524081 A2022-04-27198325P41226Espacenet
WO 2022071601 A2022-04-0736P41226Espacenet
WO 2021251504 A2021-12-1636P41226Espacenet
US 11078247 B22021-08-0312211P41226Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,151

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBA7 papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
R01AI096090Mechanism and Function of ISG1582025
P30CA021765Cancer Center Support Grant (CCSG)72025
P30CA016672Cancer Center Support Grant62025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
P30CA022453CANCER CENTER SUPPORT GRANT42025
R01GM065334Solution structure and dynamics of polyubiquitin chains42025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success42025
P20GM103430Rhode Island IDeA Network of Biomedical Research Excellence32025
P30CA010815Consolidated Basic Cancer Research Program32025

1 to 10 of 1,151Source NIH's project files

See all 1,151 nih grants

Papers1,537

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
VEXAS Syndrome: A Comprehensive Review for Dermatologists Part 1: Epidemiology, Pathophysiology, and Clinical Presentations.J Am Acad Dermatol202642607951PubTator, text miningPubMed
Vexas Syndrome Without Macrocytosis: A Case Highlighting an Expanding Clinical Phenotype and Diagnostic Delay.Cureus202642571568PubTator, text miningPubMed
Understanding protein ISGylation, a multifaceted posttranslational modification.Cell Chem Biol202642442365PubTator, text miningPubMed
ISGylation-mediated stabilization of CYP4Z1 fuels breast cancer initiation and progression.Exp Mol Med202642393313PubTator, text miningPubMed
The UBE2/E2 ubiquitin-conjugating enzyme family at the interface of tumor biology and antitumor immunity: mechanisms, biomarkers, and therapeutic opportunities.Front Immunol202642358995PubTator, text miningPubMed
Early proteomic and metabolomic signatures in diabetes associated with progression to diabetic retinopathy over 1-2 years.Front Endocrinol (Lausanne)202642358678PubTator, text miningPubMed
Mechanism of auranofin toxicity: Inhibition of tetrahydrobiopterin metabolism.Toxicol Appl Pharmacol202642334839PubTator, text miningPubMed
Myelodysplasia in VEXAS syndrome.Blood Adv202642284697PubTator, text miningPubMed
A ubiquitinated E2-based mRNA vaccine confers complete protection against lethal challenge with classical swine fever virus.J Virol202642283466PubTator, text miningPubMed
Tumor-enriched circRNA TAFCR1 drives cancer progression and metastasis by disrupting UBE1-dependent TRIM21-mediated CD44 ubiquitination.Biomark Res202642265572PubTator, text miningPubMed

1 to 10 of 1,537

See all 1,537 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7318

GET https://conductscience.org/api/genes/v1/7318/patents?page=2