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Gene · 7322

UBE2D2: ubiquitin conjugating enzyme E2 D2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UBE2D2: ubiquitin conjugating enzyme E2 D2. Genes, record 7322. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7322

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Gene

Symbol
UBE2D2
HGNC
Name
ubiquitin conjugating enzyme E2 D2
HGNC
NCBI Gene ID
7322
NCBI Gene
HGNC ID
HGNC:12475
HGNC
Ensembl
ENSG00000131508
NCBI Gene
Aliases
E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, UbcH5B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62837Ubiquitin-conjugating enzyme E2 D214762Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1911622P62837Espacenet
JP 2025517970 A2025-06-1211622P62837Espacenet
JP 2025024198 A2025-02-1916809P62837Espacenet
JP 2025024198 A2025-02-1916810P62837Espacenet
US 11884978 B22024-01-30788P62837Espacenet
JP 2023550743 A2023-12-0571P62837Espacenet
US 11446398 B22022-09-2095128P62837Espacenet
US 11446398 B22022-09-2095129P62837Espacenet
JP 2022524081 A2022-04-27198099P62837Espacenet
JP 2022524081 A2022-04-27198100P62837Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,070

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBE2D2 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)212025
P30CA008748Cancer Center Support Grant82025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control72025
P30GM124165NE-CAT: A Resource for Advanced Macromolecular Crystallography52025
R01GM065334Solution structure and dynamics of polyubiquitin chains52025
ZIABC010977Cbl Proteins as Regulators of Tyrosine Kinase Signaling52025
P30CA016672Cancer Center Support Grant42025
P30CA054174Mays Cancer Center at UT Health SA42025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital42025
R35GM128855Spindle Assembly Checkpoint Silencing42025

1 to 10 of 1,070Source NIH's project files

See all 1,070 nih grants

Papers1,418

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Structural determinants for FAT10 activation and transfer from UBA6 to E2 enzymes.Nat Commun202642733088PubTator, text miningPubMed
Integrative Bioinformatics and Machine Learning Analysis Identifies Novel Molecular Biomarkers in Prostate Adenocarcinoma.Int J Mol Sci202642589294PubTator, text miningPubMed
Chemical Synthesis of Asymmetric Nucleosomes Reveals Intramolecular Activation of UHRF1 E3 Ligase by H3K9me3.J Am Chem Soc202642485202PubTator, text miningPubMed
Analysis and validation of abnormal signaling pathways and immune cell infiltration characteristics in digestive system cancers based on peroxisome-related genes.Biol Direct202642298691PubTator, text miningPubMed
STAT3 isoform dynamics reveal robust splice ratio maintenance across cytokine-activated human immune cells.Front Immunol202641993160PubTator, text miningPubMed
OTUB1 stabilizes PRRSV matrix protein through a non-canonical deubiquitination mechanism to promote viral replication.J Virol202641914757PubTator, text miningPubMed
High-throughput discovery and characterisation of pentafluorobenzene sulfonamide modifiers of Aurora A kinase.RSC Chem Biol202641847687PubTator, text miningPubMed
Alterations in energy production in a Drosophila model for the X-linked dystonia-parkinsonism-related Taf1 deficiency.Front Aging Neurosci202641777671PubTator, text miningPubMed
Non-hydrolyzable acetyllysine analogs to study protein acetylation in vitro and in cells.Nat Commun202641723125PubTator, text miningPubMed
Role and underlying mechanisms of miR‑200 family in breast cancer (Review).Int J Oncol202641716019PubTator, text miningPubMed

1 to 10 of 1,418

See all 1,418 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7322

GET https://conductscience.org/api/genes/v1/7322/patents?page=2