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Gene · 7323

UBE2D3: ubiquitin conjugating enzyme E2 D3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UBE2D3: ubiquitin conjugating enzyme E2 D3. Genes, record 7323. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7323

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Gene

Symbol
UBE2D3
HGNC
Name
ubiquitin conjugating enzyme E2 D3
HGNC
NCBI Gene ID
7323
NCBI Gene
HGNC ID
HGNC:12476
HGNC
Ensembl
ENSG00000109332
NCBI Gene
Aliases
E2(17)KB3, UBC4/5, UBCH5C, UbcH5C
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P61077Ubiquitin-conjugating enzyme E2 D314747Ensembl, GeneID, HGNC

Source UniProt

Patents109

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195196P61077Espacenet
JP 2025517970 A2025-06-125196P61077Espacenet
JP 2023550743 A2023-12-0572P61077Espacenet
US 11630109 B22023-04-1833P61077Espacenet
US 11459613 B22022-10-0454P61077Espacenet
US 11446398 B22022-09-2095133P61077Espacenet
US 11446398 B22022-09-2095134P61077Espacenet
US 11446398 B22022-09-2095136P61077Espacenet
US 11446398 B22022-09-2095139P61077Espacenet
US 11446398 B22022-09-2095140P61077Espacenet

1 to 10 of 109

See all 109 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,290

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBE2D3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant62025
R01CA132878Post-translational Modifications in DNA Damage Response: a Structural Perspective62025
P30CA008748Cancer Center Support Grant52025
P30CA016056Roswell Park Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025
R01CA074305Chemical Approaches to Cell Signaling Enzymes52025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias42025
P30CA016087Cancer Center Support Grant42025
P51OD011092Support for National Primate Research Center42025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control42025

1 to 10 of 1,290Source NIH's project files

See all 1,290 nih grants

Papers1,394

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Cryo-EM structure, enzymatic activity and genome targeting of canonical PRC1.Nat Struct Mol Biol202642736418PubTator, text miningPubMed
M2‑TAM‑derived exosomal miR‑491‑3p modulates UBE2D3 and promotes the proliferation, migration and invasion of lung cancer cells.Oncol Rep202642495775PubTator, text miningPubMed
Small Structural Variations, Large Functional Consequences: Comparative Analysis Reveals Structural Control of Ubiquitylation Site Selection by BRCA1/BARD1.bioRxiv202642427510PubTator, text miningPubMed
Cytoplasmic lattices store developmentally poised degradative and cytoskeletal complexes in mammalian eggs.Nat Struct Mol Biol202642426369PubTator, text miningPubMed
Retraction Note: UBE2D3 regulated by WTAP-mediated m6A modification inhibits temozolomide chemosensitivity in glioblastoma.Naunyn Schmiedebergs Arch Pharmacol202642337166PubTator, text miningPubMed
Dual IRE1 targets: Determinants of the cell fate?FEBS J202642298872PubTator, text miningPubMed
Genetic associations between asthma and type 2 inflammatory diseases: Insights from pleiotropic loci and genes: shared genetics of Type 2 Iinflammatory diseases: Shared Genetics of Type 2 Inflammatory Diseases.
Hum Immunol202642143449PubTator, text miningPubMed
Uncovering core stemness biomarkers in HBV-HCC through integrated multi-omics.PLoS One202642133686PubTator, text miningPubMed
NUDT21 Drives T-Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation.Adv Sci (Weinh)202641926643PubTator, text miningPubMed
Molecular basis of oocyte cytoplasmic lattice assembly.Nature202641845018PubTator, text miningPubMed

1 to 10 of 1,394

See all 1,394 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7323

GET https://conductscience.org/api/genes/v1/7323/patents?page=2