ConductScience.org, home

Gene · 7332

UBE2L3: ubiquitin conjugating enzyme E2 L3

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. UBE2L3: ubiquitin conjugating enzyme E2 L3. Genes, record 7332. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7332

On this page

Gene

Symbol
UBE2L3
HGNC
Name
ubiquitin conjugating enzyme E2 L3
HGNC
NCBI Gene ID
7332
NCBI Gene
HGNC ID
HGNC:12488
HGNC
Ensembl
ENSG00000185651
NCBI Gene
Aliases
E2-F1, L-UBC, UBCH7, UbcM4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P68036Ubiquitin-conjugating enzyme E2 L315421Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469077P68036Espacenet
EP 4650780 A22025-11-196880P68036Espacenet
JP 2025517970 A2025-06-126880P68036Espacenet
EP 4463571 A12024-11-20265P68036Espacenet
JP 2023550743 A2023-12-0585P68036Espacenet
JP 2023504790 A2023-02-0715P68036Espacenet
US 11446398 B22022-09-2095243P68036Espacenet
JP 2022524081 A2022-04-27198214P68036Espacenet
JP 2021525807 A2021-09-2711P68036Espacenet
EP 3805256 A12021-04-1411P68036Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,230

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBE2L3 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)162025
R01AI024717Genetic Linkage in Lupus82025
R01AR063759Defining the influence of RA genetic susceptibility factors on T cell antigen specificity and functional state72025
U54GM104938Oklahoma Shared Clinical and Translational Resources62025
P30CA016672Cancer Center Support Grant52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
ZIABC010440Protein Structure, Stability, and Amyloid Formation52025
ZIABC010441Biomolecular Recognition and Binding Mechanisms52025
P30CA014195Cancer Center Support Grant (CCSG)42025
U01DK062423Genomic and Immunologic Characterization of Inflammatory Bowel Disease and its Phenotypes42025

1 to 10 of 1,230Source NIH's project files

See all 1,230 nih grants

Papers1,458

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Fluorophore placement and size impact E2 ubiquitination efficiency.Biochem J202642770861PubTator, text miningPubMed
Integrative analysis of gastric tissue transcriptomes and gastric cancer GWAS implicates candidate susceptibility genes.Am J Hum Genet202642392035PubTator, text miningPubMed
In vivo CRISPR/Cas9 Screening Reveals that UBE2L3 Modulates Autophagic Flux through TSC2 Ubiquitination and Potentiates PD-1 Blockade in Triple-Negative Breast Cancer.Int J Biol Sci202641943836PubTator, text miningPubMed
Meta-Analysis of Genetic Variants Associated With HBV Infection Susceptibility and Hepatocellular Carcinoma Risk.J Viral Hepat202641937404PubTator, text miningPubMed
Transcriptome sequencing (RNA-Seq) reveals non-coding pseudogene CDC27P9 role in cervical cancer.Apoptosis202641874705PubTator, text miningPubMed
TRIM proteins as emerging regulators of immune pathways: potential therapeutic targets in immune-related disorders.Front Immunol202641756277PubTator, text miningPubMed
"Lys-Leu" Motif Empowers Expedient OaAEP1-Catalyzed Generation of N‑Terminal Cysteine Recombinant Proteins for Bioconjugation and Semisynthesis.JACS Au202641755832PubTator, text miningPubMed
SMURF1 Downregulation Highlights Its Potential Role in Breast Cancer.Int J Mol Sci202641752056PubTator, text miningPubMed
Structure-guided analysis and prediction of human E2-E3 ligase pairing specificity.bioRxiv202641726935PubTator, text miningPubMed
The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation.bioRxiv202641542392PubTator, text miningPubMed

1 to 10 of 1,458

See all 1,458 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7332

GET https://conductscience.org/api/genes/v1/7332/patents?page=2