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Gene · 7335

UBE2V1: ubiquitin conjugating enzyme E2 V1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UBE2V1: ubiquitin conjugating enzyme E2 V1. Genes, record 7335. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7335

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Gene

Symbol
UBE2V1
HGNC
Name
ubiquitin conjugating enzyme E2 V1
HGNC
NCBI Gene ID
7335
NCBI Gene
HGNC ID
HGNC:12494
HGNC
Ensembl
ENSG00000244687
NCBI Gene
Aliases
CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13404Ubiquitin-conjugating enzyme E2 variant 11474Ensembl, GeneID, HGNC

Source UniProt

Patents17

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469040Q13404Espacenet
EP 4650780 A22025-11-198993Q13404Espacenet
JP 2025517970 A2025-06-128993Q13404Espacenet
US 11892452 B22024-02-0631Q13404Espacenet
JP 2023550743 A2023-12-0599Q13404Espacenet
US 11446398 B22022-09-2095075Q13404Espacenet
US 11400116 B22022-08-02741Q13404Espacenet
JP 2022524081 A2022-04-27198046Q13404Espacenet
US 11078247 B22021-08-0312246Q13404Espacenet
US 11016093 B22021-05-2531Q13404Espacenet

1 to 10 of 17

See all 17 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,183

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBE2V1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant132025
P30CA010815Consolidated Basic Cancer Research Program52025
P30CA008748Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
R01AI060025From Drosophila Immunity to Anti-Inflammatories42025
P01CA019014Viral Oncogenesis, Latency, and Replication32025
P40OD010440Caenorhabditis Genetics Center32025
R01DE017336Epigenetic Regulation of Epstein-Barr Virus32025
R01GM065334Solution structure and dynamics of polyubiquitin chains32025
UL1TR001863Yale Clinical and Translational Science Award32025

1 to 10 of 1,183Source NIH's project files

See all 1,183 nih grants

Papers1,504

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Type I collagen promotes triple-negative breast cancer progression through a UBE2V1-ACSL5 regulatory axis.Front Oncol202642755793PubTator, text miningPubMed
Small-molecule disruption of the TRAF6-Ubc13 protein-protein interaction: targeting noncanonical ubiquitin signaling in inflammation and cancer.Biochem Pharmacol202642660298PubTator, text miningPubMed
BRD4-mediated histone H4K12 lactylation drives ovarian cancer progression by activating the Ube2v1-DDX3X ubiquitination axis.J Transl Med202642374413PubTator, text miningPubMed
BMS-CTMC-2025-461Ubiquitin as a Putative Causal Immune Orchestrator in Initial COVID-19 Severity: A Mendelian Randomization and Multi-Omics Study.Curr Top Med Chem202642300294PubTator, text miningPubMed
CircRNA-cZFR is upregulated in bladder cancer and promotes tumorigenesis via UBE2V1 regulation.Sci Rep202642215525PubTator, text miningPubMed
CBX2 phase-separation contributes to homologous recombination repair and drug resistance in ovarian cancer.Cell Death Dis202641888115PubTator, text miningPubMed
Moonlighting cytosolic function of ACAD9: suppression of TRAF6-mediated osteoclastogenesis and protection against osteoporosis.Cell Death Dis202641888097PubTator, text miningPubMed
Uev1A counteracts oncogenic Ras stimuli in both polyploid and diploid cells.Elife202641879050PubTator, text miningPubMed
EpCAM-PSMA: Potential predictors of treatment outcomes for PSMA-targeted alpha therapies in metastatic castration-resistant prostate cancer.Mol Ther Oncol202641732759PubTator, text miningPubMed
The impact of p53 mutation on tumor immune evasion: mechanistic insights and clinical implications.Front Immunol202641727427PubTator, text miningPubMed

1 to 10 of 1,504

See all 1,504 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7335

GET https://conductscience.org/api/genes/v1/7335/patents