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Gene · 7337

UBE3A: ubiquitin protein ligase E3A

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. UBE3A: ubiquitin protein ligase E3A. Genes, record 7337. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/7337

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
UBE3A
HGNC
Name
ubiquitin protein ligase E3A
HGNC
NCBI Gene ID
7337
NCBI Gene
HGNC ID
HGNC:12496
HGNC
Ensembl
ENSG00000114062
NCBI Gene
Aliases
ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A, PIX1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q05086Ubiquitin-protein ligase E3A87525Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468952Q05086Espacenet
EP 4641201 A22025-10-2925402Q05086Espacenet
JP 2025148578 A2025-10-0710Q05086Espacenet
JP 2025529142 A2025-09-045150Q05086Espacenet
JP 2025111747 A2025-07-30138Q05086Espacenet
US 12371689 B22025-07-295150Q05086Espacenet
JP 2025517969 A2025-06-1225402Q05086Espacenet
WO 2025101862 A12025-05-1528Q05086Espacenet
JP 2024178415 A2024-12-24527Q05086Espacenet
JP 2024178415 A2024-12-24528Q05086Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,489

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
R01CA142861Renewal: HPV and the DNA Damage Response142025
T32HD040127Postdoctoral Research in Neurodevelopmental Disorders142025
ZIABC011490Maintaining cell health by targeted protein degradation112025
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses102025
P30CA016672Cancer Center Support Grant92025
P50HD103573Clinical Translational Research Center for Neurodevelopmental Disorders92025
P30CA008748Cancer Center Support Grant82025
P30CA016086Cancer Center Support Grant82025
ZIASC010357Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses82025
P40OD018537Bloomington Drosophila Stock Center at Indiana University72025

1 to 10 of 2,489Source NIH's project files

See all 2,489 nih grants

Papers4,306

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42809130PubTator, text miningPubMed
42806301PubTator, text miningPubMed
42782803PubTator, text miningPubMed
42768751PubTator, text miningPubMed
42733627PubTator, text miningPubMed
42642544PubTator, text miningPubMed
42607587PubTator, text miningPubMed
42566383PubTator, text miningPubMed
42474857PubTator, text miningPubMed
42464451PubTator, text miningPubMed

1 to 10 of 4,306

See all 4,306 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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