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UCP2: uncoupling protein 2

1 protein, 59 patents, 0 drugs, 0 trials, 2,280 NIH grants and 5,422 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolUCP2HGNC
Nameuncoupling protein 2HGNC
NCBI Gene ID7351NCBI Gene
HGNC IDHGNC:12518HGNC
EnsemblENSG00000175567NCBI Gene
AliasesBMIQ4, SLC25A8, UCPHNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P55851Dicarboxylate carrier SLC25A83090Ensembl, GeneID, HGNCUniProt

Patents 59

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469303P55851Espacenet
EP 4650780 A22025-11-194802P55851Espacenet
EP 4620519 A22025-09-242P55851Espacenet
EP 4620520 A22025-09-242P55851Espacenet
EP 4620521 A22025-09-242P55851Espacenet
JP 2025517970 A2025-06-124802P55851Espacenet
JP 2025032204 A2025-03-1137963P55851Espacenet
EP 4461818 A22024-11-1337963P55851Espacenet
JP 2024112982 A2024-08-214414P55851Espacenet
JP 2023058610 A2023-04-2537963P55851Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2280

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK056341Washington University Nutrition Obesity Research Center102,025NIH's project files
P30DK019525University of Pennsylvania Diabetes Research Center82,025NIH's project files
P30DK020579Diabetes Research Center62,025NIH's project files
P30CA008748Cancer Center Support Grant52,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)52,025NIH's project files
P30DK056336UAB Nutrition Obesity Research Center (NORC)52,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility52,025NIH's project files
P30AG028740University of Florida Older Americans Independence Center (OAIC)42,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)42,025NIH's project files
P30DK072476Pennington/Louisiana NORC42,025NIH's project files

Papers 5422

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42753462PubTator, text miningPubMed
42692239PubTator, text miningPubMed
42680753PubTator, text miningPubMed
42639042PubTator, text miningPubMed
42572219PubTator, text miningPubMed
42534632PubTator, text miningPubMed
42500560PubTator, text miningPubMed
42431566PubTator, text miningPubMed
42351126PubTator, text miningPubMed
42309513PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license