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Gene · 7352

UCP3: uncoupling protein 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UCP3: uncoupling protein 3. Genes, record 7352. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7352

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Gene

Symbol
UCP3
HGNC
Name
uncoupling protein 3
HGNC
NCBI Gene ID
7352
NCBI Gene
HGNC ID
HGNC:12519
HGNC
Ensembl
ENSG00000175564
NCBI Gene
Aliases
SLC25A9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P55916Putative mitochondrial transporter UCP33120Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026215372 A12026-10-154P55916Espacenet
EP 4821507 A12026-10-144P55916Espacenet
JP 2026004568 A2026-01-1469305P55916Espacenet
EP 4620519 A22025-09-243P55916Espacenet
EP 4620520 A22025-09-243P55916Espacenet
EP 4620521 A22025-09-243P55916Espacenet
US 11446398 B22022-09-2095800P55916Espacenet
JP 2022524081 A2022-04-27198771P55916Espacenet
US 11078247 B22021-08-0312289P55916Espacenet
US 10668104 B22020-06-026P55916Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,050

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUCP3 papersNewest fiscal year
P30DK056336UAB Nutrition Obesity Research Center (NORC)122025
P30DK072476Pennington/Louisiana NORC82025
P30DK045735Yale Diabetes Research Center72025
P30DK079626UAB Diabetes Research Center62025
P30DK056341Washington University Nutrition Obesity Research Center52025
P30DK020579Diabetes Research Center42025
T32DK007352Diabetes and Metabolism42025
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures42025
P30DK026687New York Obesity Research Center32025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)32025

1 to 10 of 1,050Source NIH's project files

See all 1,050 nih grants

Papers2,365

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Whole-exome sequencing-centered genetic evaluation for early-onset obesity in Chinese children: a retrospective single-center cohort.Transl Pediatr202642724349PubTator, text miningPubMed
Cardiometabolic disease risk: the joint role of the UCP1, UCP2, UCP3, and FTO gene variants.Biochimie202642692239PubTator, text miningPubMed
[Association of UCP1 rs1800592, UCP2 rs660339, and UCP3 rs1800849 polymorphisms with body mass index and lipid metabolism parameters in the indigenous population of the North of Western Siberia].Vopr Pitan202642572219PubTator, text miningPubMed
Selective Small-Molecule AdipoR1 Agonist 3-Hydroxy Pterocarpan Salt (CDRI-1709S) Ameliorates Skeletal Muscle Atrophy.J Cachexia Sarcopenia Muscle202642480512PubTator, text miningPubMed
Sarcolipin-SERCA uncoupling as a plausible heat source for sustaining fever.Front Physiol202642422364PubTator, text miningPubMed
Impact of per- and polyfluoroalkyl substances (PFAS) on brain development and function.Behav Brain Res202642361859PubTator, text miningPubMed
Effect of six weeks ubiquinol supplementation on mitochondrial respiratory function and exercise capacity in healthy males.Eur J Appl Physiol202642249931PubTator, text miningPubMed
Personalized Profiles of Autonomic Regulation in Elite Athletes: Analysis of Genetic and Cardiorespiratory Determinants Using Decision Tree Modeling.J Pers Med202642042597PubTator, text miningPubMed
The association between dietary intakes of nitrate and nitrite and odds of metabolic syndrome and its component in adults.Sci Rep202641888168PubTator, text miningPubMed
Cold exposure and human metabolism: A heterogeneous response across tissues and organs.Temperature (Austin)202641797814PubTator, text miningPubMed

1 to 10 of 2,365

See all 2,365 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7352

GET https://conductscience.org/api/genes/v1/7352/patents?page=2