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Gene · 7369

UMOD: uromodulin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UMOD: uromodulin. Genes, record 7369. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7369

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Gene

Symbol
UMOD
HGNC
Name
uromodulin
HGNC
NCBI Gene ID
7369
NCBI Gene
HGNC ID
HGNC:12559
HGNC
Ensembl
ENSG00000169344
NCBI Gene
Aliases
ADMCKD2, ADTKD1, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07911Uromodulin64010Ensembl, GeneID, HGNC

Source UniProt

Patents74

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469377P07911Espacenet
JP 2026004568 A2026-01-1469379P07911Espacenet
JP 2026004568 A2026-01-1469380P07911Espacenet
EP 4650780 A22025-11-194410P07911Espacenet
EP 4640849 A22025-10-29582P07911Espacenet
EP 4641201 A22025-10-293957P07911Espacenet
JP 2025534663 A2025-10-1710P07911Espacenet
JP 2025147176 A2025-10-0613935P07911Espacenet
JP 2025147176 A2025-10-0613936P07911Espacenet
WO 2025193807 A12025-09-183P07911Espacenet

1 to 10 of 74

See all 74 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,821

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUMOD papersNewest fiscal year
UL1TR001863Yale Clinical and Translational Science Award182025
I01BX003935The immunomodulatory function of Tamm-Horsfall protein in acute kidney injury132025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal102025
R01DK093770Novel Kidney Injury Tools in Deceased Organ Donation to Predict Graft Outcomes92025
R01AG034853Biomarker-Based Diagnostic Algorithms To Prevent, Detect And Guide Treatment Of Kidney Disease In Persons Living With HIV82025
P30DK063491Diabetes Research Center (DRC)72025
UL1TR001881UCLA Clinical and Translational Science Institute72025
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair62025
R01DK076077Adaptive and maladaptive repair after kidney injury62025
R01DK078244Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes62025

1 to 10 of 1,821Source NIH's project files

See all 1,821 nih grants

Papers3,273

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Beyond creatinine: biomarkers of kidney recovery after acute kidney injury.Curr Opin Nephrol Hypertens202642817189PubTator, text miningPubMed
Serum Uromodulin in Dialysis Patients.Clin J Am Soc Nephrol202642809344PubTator, text miningPubMed
Temporal dynamics of urinary extracellular vesicle excretion and cargo in healthy subjects over 24 h.Am J Physiol Renal Physiol202642775544PubTator, text miningPubMed
Endocrine regulation of uromodulin in aging.Front Endocrinol (Lausanne)202642755824PubTator, text miningPubMed
From Guidelines to Practice: Pilot Implementation and Analytical Boundaries of a Focused ADPKD-Spectrum Gene Panel.Diagnostics (Basel)202642739200PubTator, text miningPubMed
Urinary Uromodulin for Distinguishing Between Glomerulonephritis, Diabetic Kidney Disease, and Nephrosclerosis in a Biopsy-Proven Cohort.Diagnostics (Basel)202642739170PubTator, text miningPubMed
Predictive Value of Urine Tubular Biomarkers on Kidney Outcomes: Observations from EMPA-KIDNEY.Clin J Am Soc Nephrol202642690923PubTator, text miningPubMed
Metabolomic Signatures of Inflammation in Chronic Kidney Disease.Kidney Med202642668601PubTator, text miningPubMed
MANF clears mutant uromodulin in human kidney organoids of autosomal dominant tubulointerstitial kidney disease.J Clin Invest202642640736PubTator, text miningPubMed
Uromodulin T62P variant causes kidney tubular stress and injury modulated by age and polygenic risk.medRxiv202642619988PubTator, text miningPubMed

1 to 10 of 3,273

See all 3,273 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7369

GET https://conductscience.org/api/genes/v1/7369/patents?page=2