Gene · 7378
UPP1: uridine phosphorylase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. UPP1: uridine phosphorylase 1. Genes, record 7378. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7378
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16831 | Uridine phosphorylase 1 | 310 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents51
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69353 | Q16831 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 69354 | Q16831 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 69355 | Q16831 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5836 | Q16831 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5549 | Q16831 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5549 | Q16831 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5836 | Q16831 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 38002 | Q16831 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 38006 | Q16831 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 38002 | Q16831 | Espacenet |
1 to 10 of 51
See all 51 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants976
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | UPP1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 3 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 3 | 2025 |
| P50CA058223 | SPORE in Breast Cancer | 3 | 2025 |
| R01GM098535 | Molecular mechanisms of DNA damage signaling and repair | 3 | 2025 |
| T32CA067754 | Cancer Biology, Informatics & Omics (CBIO) Training Program | 3 | 2025 |
| P01CA163222 | Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment | 2 | 2025 |
1 to 10 of 976Source NIH's project files
See all 976 nih grantsPapers1,570
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Clinical evaluation of a novel urinary protein competitive immunoassay in the detection of proteinuria in adults with sickle cell disease. | Front Med (Lausanne) | 2026 | 42745797 | PubTator, text mining | PubMed |
| UPP1 as a Diagnostic Biomarker: Insights from Integrative Bioinformatics and Immune Infiltration Analyses in COPD. | J Vis Exp | 2026 | 42695583 | PubTator, text mining | PubMed |
| UPP1 in Cancer: Context-Dependent Roles in Metabolic Adaptation and Treatment Response. | Curr Issues Mol Biol | 2026 | 42651811 | PubTator, text mining | PubMed |
| Integration of RNA-seq and scRNA-seq to investigate the role of cell cycle-related biomarkers in sepsis. | PLoS One | 2026 | 42579704 | PubTator, text mining | PubMed |
| Comparative Analysis of LPS/IFN-γ and LPS/ATP-Induced Inflammatory Models in BV2 Microglia. | Neurochem Res | 2026 | 42566061 | PubTator, text mining | PubMed |
| Targeted Transcriptomic Profiling Identifies Biomarkers and Molecular Features Associated With Immunotherapy Response in Classic Hodgkin Lymphoma. | Mod Pathol | 2026 | 42556471 | PubTator, text mining | PubMed |
| Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer. | PLoS One | 2026 | 42536695 | PubTator, text mining | PubMed |
| Enhanced oral absorption and anti-colorectal cancer efficacy of trifluridine by interfering with both TPase and UPase. | Bioorg Chem | 2026 | 42424926 | PubTator, text mining | PubMed |
| Integrative Single-Cell and Bulk Transcriptome Analysis Reveals Molecular Mechanisms, Prognostic Signatures, and Therapeutic Response in Glioma. | J Craniofac Surg | 2026 | 42412600 | PubTator, text mining | PubMed |
| Upregulation of macrophage UPP1 promotes lung adenocarcinoma metastasis through an mtROS-cGAS-NLRP3 inflammasome axis. | Cell Death Discov | 2026 | 42409780 | PubTator, text mining | PubMed |
1 to 10 of 1,570
See all 1,570 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7378
GET https://conductscience.org/api/genes/v1/7378/patents?page=2