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Gene · 7389

UROD: uroporphyrinogen decarboxylase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UROD: uroporphyrinogen decarboxylase. Genes, record 7389. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7389

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Gene

Symbol
UROD
HGNC
Name
uroporphyrinogen decarboxylase
HGNC
NCBI Gene ID
7389
NCBI Gene
HGNC ID
HGNC:12591
HGNC
Ensembl
ENSG00000126088
NCBI Gene
Aliases
PCT, UPD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P06132Uroporphyrinogen decarboxylase36719Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21143P06132Espacenet
JP 2026004568 A2026-01-1469405P06132Espacenet
EP 4650780 A22025-11-191190P06132Espacenet
JP 2025517970 A2025-06-121190P06132Espacenet
JP 2023521663 A2023-05-25142P06132Espacenet
US 11446398 B22022-09-2095990P06132Espacenet
JP 2022524081 A2022-04-27198961P06132Espacenet
JP 2021530985 A2021-11-18250P06132Espacenet
WO 2021202604 A12021-10-07143P06132Espacenet
JP 2019054813 A2019-04-11249840P06132Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants496

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUROD papersNewest fiscal year
P30CA042014Cancer Center Support Grant72025
U54DK110858Center for Iron & Heme Disorders at the University of Utah62025
P30CA008748Cancer Center Support Grant32025
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment32025
R01DK074797Inter-organ signaling in heme metabolism and organismal homeostasis.32025
K23AR079586Measuring and Understanding Light Sensitivity in Erythropoietic Protoporphyria22025
P20GM113132The Institute for Biomolecular Targeting22025
P30CA030199Cancer Center Support Grant (CCSG)22025
P30DK034854Integrated Epithelial and Muscosal Biology22025
R01DK067859Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity22025

1 to 10 of 496Source NIH's project files

See all 496 nih grants

Papers2,652

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Humanin Attenuates Inflammatory Liver Injury and NF-κB Activation During Systemic Hypervirulent Klebsiella pneumoniae Infection.Pathogens202642796734PubTator, text miningPubMed
A Candidate MEST Splice-Site Variant in a Patient with Silver-Russell Syndrome-like Phenotype: First Report and Literature Review.Genes (Basel)202642792886PubTator, text miningPubMed
Association of serum inflammatory factors and hematologic parameters with lower limb deep vein thrombosis in neurocritical patients: A retrospective cohort study.J Med Biochem202642775043PubTator, text miningPubMed
Effect of loading dose atorvastatin on postoperative cardiovascular events in elderly patients with acute myocardial infarction undergoing percutaneous coronary intervention.Am J Transl Res202642769353PubTator, text miningPubMed
Dietary advanced glycation end products intake and osteoporosis risk in adults with type 2 diabetes mellitus.Medicine (Baltimore)202642736800PubTator, text miningPubMed
Effect of lactate/albumin ratio on mortality in patients aged ≥ 65 years with community-acquired pneumonia.J Infect Dev Ctries202642715283PubTator, text miningPubMed
Acute Intermittent Porphyria with a Secondary Porphyria Cutanea Tarda-like Biochemical Pattern in a Patient with Co-Morbid Human Immunodeficiency Virus Infection.EJIFCC202642698978PubTator, text miningPubMed
[Construct a nomogram prediction model for septic shock in patients with sepsis based on serum sphingosine-1-phosphate, microRNA-155-5p and soluble suppression of tumorigenicity 2 protein].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue202642693964PubTator, text miningPubMed
Oxidation of Uroporphyrinogens During Heme Synthesis: Role of Iron, Susceptibility and Consequences.Biomolecules202642650854PubTator, text miningPubMed
Interleukin-6 as a sepsis biomarker in neonatal and pediatric care: A retrospective real world cohort study.Eur J Pediatr202642622709PubTator, text miningPubMed

1 to 10 of 2,652

See all 2,652 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7389

GET https://conductscience.org/api/genes/v1/7389/patents?page=2