Gene · 7391
USF1: upstream transcription factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. USF1: upstream transcription factor 1. Genes, record 7391. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7391
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P22415 | Upstream stimulatory factor 1 | 310 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69343 | P22415 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 69344 | P22415 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8347 | P22415 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15825 | P22415 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8347 | P22415 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15825 | P22415 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15825 | P22415 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15664 | P22415 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 95864 | P22415 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 95865 | P22415 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,889
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | USF1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| R01CA051497 | Defining the Role of the Cancer Circadian Clock in Tumor Immunity and Tumorigenesis | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 5 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 4 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 4 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,889Source NIH's project files
See all 1,889 nih grantsPapers2,490
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Seven Homologous Regions from a Novel Bombyx mori Nucleopolyhedrovirus (YT Strain) Isolate Enhance Early and Late Viral Promoters In Vitro and In Vivo. | Insects | 2026 | 42652436 | PubTator, text mining | PubMed |
| Proteome-wide Multi-omics Profiling of Osteosarcoma Transcription Factor Networks. | J Mol Biol | 2026 | 42526587 | PubTator, text mining | PubMed |
| USF1-mediated transcription of PARP1 contributes to sevoflurane-induced pyroptosis in perioperative neurocognitive disorders. | Funct Integr Genomics | 2026 | 42521865 | PubTator, text mining | PubMed |
| HLA class I-naturally presented synovial tissue peptides are recognized by CD8+ T lymphocytes from rheumatoid arthritis patients. | Front Immunol | 2026 | 42490907 | PubTator, text mining | PubMed |
| Dibromoacetic acid impairs spermatogenesis: integrative evidence from human epidemiology, network toxicology, and mechanistic validation. | Environ Int | 2026 | 42468183 | PubTator, text mining | PubMed |
| EFO2 promotes triple-negative breast cancer progression and reduces CD8+ T cell-mediated killing by acetylating USF1 to enhance SLC2A1-mediated glycolysis. | Biochem Pharmacol | 2026 | 42456828 | PubTator, text mining | PubMed |
| Arsenic trioxide triggers ferroptosis in neuroblastoma via USF1/GPX4 axis. | Bioorg Chem | 2026 | 42322906 | PubTator, text mining | PubMed |
| LncRNA MIR4435-2HG-mediated succinylation of USF1 promotes its protein stability and induces epithelial-mesenchymal transition in HNSCC. | Epigenetics | 2026 | 42132011 | PubTator, text mining | PubMed |
| Hydrogen-Bond-Directed Assembly of Urea Derivatives: Exceptional Birefringence Achieved by π-Conjugated Unit Alignment. | Small | 2026 | 41979121 | PubTator, text mining | PubMed |
| USF1 transcriptionally activates TRIM55 to promote diabetic cardiomyopathy progression by enhancing HSPB1 protein degradation. | J Bioenerg Biomembr | 2026 | 41961164 | PubTator, text mining | PubMed |
1 to 10 of 2,490
See all 2,490 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7391
GET https://conductscience.org/api/genes/v1/7391/patents?page=2