Gene · 7399
USH2A: usherin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. USH2A: usherin. Genes, record 7399. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7399
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75445 | Usherin | 5,202 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents35
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 49 | O75445 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 69423 | O75445 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3926 | O75445 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5207 | O75445 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5207 | O75445 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3926 | O75445 | Espacenet |
| US 12246072 B2 | 2025-03-11 | 38 | O75445 | Espacenet |
| WO 2025036833 A1 | 2025-02-20 | 3 | O75445 | Espacenet |
| EP 4491229 A2 | 2025-01-15 | 306 | O75445 | Espacenet |
| WO 2024230934 A1 | 2024-11-14 | 431 | O75445 | Espacenet |
1 to 10 of 35
See all 35 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,190
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | USH2A papers | Newest fiscal year |
|---|---|---|---|
| R01EY018213 | Defining Barriers to Gene Therapy | 22 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 15 | 2025 |
| P30EY014104 | P30 Core Grant for Vision Research | 15 | 2025 |
| R01DC012049 | Optimizing Genetic Testing for Deafness for Clinical Diagnostics | 14 | 2025 |
| R01EY022356 | Molecular Basis of Human Visual System Disorders | 14 | 2025 |
| R01EY024698 | Gene Editing and Silencing in Phototransduction | 14 | 2025 |
| P30EY014800 | University of Utah Core Vision Research Grant | 13 | 2025 |
| R01EY018571 | Genetics of early onset retinal diseases | 12 | 2025 |
| R01EY012910 | Precision Medicine for Inherited Retinal Degenerations | 9 | 2025 |
| P30EY022589 | NEI Center Core Grant for Vision Research | 8 | 2025 |
1 to 10 of 1,190Source NIH's project files
See all 1,190 nih grantsPapers2,630
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Clinical and Population-Specific Insights Into Inherited Retinal Dystrophies From Whole-Exome Sequencing of the Polish Cohort. | Invest Ophthalmol Vis Sci | 2026 | 42803640 | PubTator, text mining | PubMed |
| Early Molecular Testing for Presumptive Genetic Eye Diseases. | Genes (Basel) | 2026 | 42792986 | PubTator, text mining | PubMed |
| Fundus albipunctatus-like retinopathy in hypovitaminosis A-related optic neuropathy with skull hyperostosis. | BMJ Case Rep | 2026 | 42785777 | PubTator, text mining | PubMed |
| Deep Learning for Diagnosis of Choroideremia and USH2A-Associated Rod-Cone Dystrophy Using Macular OCT Volumes. | Ophthalmol Sci | 2026 | 42775014 | PubTator, text mining | PubMed |
| Genetic Sequencing in Saudi Patients with Systemic Lupus Erythematosus. | Open Access Rheumatol | 2026 | 42770033 | PubTator, text mining | PubMed |
| Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune-Shielded Heart Valves. | Adv Healthc Mater | 2026 | 42765550 | PubTator, text mining | PubMed |
| Generation of isogenic gene-corrected cell lines from a USH2A-RP patient-derived iPS cell line. | Stem Cell Res | 2026 | 42710431 | PubTator, text mining | PubMed |
| Whole-Exome Sequencing in a Consanguinity-Enriched South Indian Retinitis Pigmentosa Cohort: Diagnostic Yield and Molecular Spectrum. | Ophthalmol Sci | 2026 | 42701422 | PubTator, text mining | PubMed |
| USH2A-Associated Retinitis Pigmentosa in Koreans: Molecular Genetics and Clinical Characteristics. | Am J Ophthalmol | 2026 | 42692131 | PubTator, text mining | PubMed |
| Characterizing the non-pigmented retinitis pigmentosa in a Chinese cohort: Insights into phenotype, genotype, and disease progression. | Adv Ophthalmol Pract Res | 2026 | 42668498 | PubTator, text mining | PubMed |
1 to 10 of 2,630
See all 2,630 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7399
GET https://conductscience.org/api/genes/v1/7399/patents?page=2