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Gene · 7399

USH2A: usherin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. USH2A: usherin. Genes, record 7399. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7399

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Gene

Symbol
USH2A
HGNC
Name
usherin
HGNC
NCBI Gene ID
7399
NCBI Gene
HGNC ID
HGNC:12601
HGNC
Ensembl
ENSG00000042781
NCBI Gene
Aliases
RP39, US2, USH2, USHRN, dJ1111A8.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75445Usherin5,2020Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-1949O75445Espacenet
JP 2026004568 A2026-01-1469423O75445Espacenet
EP 4641201 A22025-10-293926O75445Espacenet
JP 2025529142 A2025-09-045207O75445Espacenet
US 12371689 B22025-07-295207O75445Espacenet
JP 2025517969 A2025-06-123926O75445Espacenet
US 12246072 B22025-03-1138O75445Espacenet
WO 2025036833 A12025-02-203O75445Espacenet
EP 4491229 A22025-01-15306O75445Espacenet
WO 2024230934 A12024-11-14431O75445Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,190

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUSH2A papersNewest fiscal year
R01EY018213Defining Barriers to Gene Therapy222025
P30CA013696Cancer Center Support Grant152025
P30EY014104P30 Core Grant for Vision Research152025
R01DC012049Optimizing Genetic Testing for Deafness for Clinical Diagnostics142025
R01EY022356Molecular Basis of Human Visual System Disorders142025
R01EY024698Gene Editing and Silencing in Phototransduction142025
P30EY014800University of Utah Core Vision Research Grant132025
R01EY018571Genetics of early onset retinal diseases122025
R01EY012910Precision Medicine for Inherited Retinal Degenerations92025
P30EY022589NEI Center Core Grant for Vision Research82025

1 to 10 of 1,190Source NIH's project files

See all 1,190 nih grants

Papers2,630

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical and Population-Specific Insights Into Inherited Retinal Dystrophies From Whole-Exome Sequencing of the Polish Cohort.Invest Ophthalmol Vis Sci202642803640PubTator, text miningPubMed
Early Molecular Testing for Presumptive Genetic Eye Diseases.Genes (Basel)202642792986PubTator, text miningPubMed
Fundus albipunctatus-like retinopathy in hypovitaminosis A-related optic neuropathy with skull hyperostosis.BMJ Case Rep202642785777PubTator, text miningPubMed
Deep Learning for Diagnosis of Choroideremia and USH2A-Associated Rod-Cone Dystrophy Using Macular OCT Volumes.Ophthalmol Sci202642775014PubTator, text miningPubMed
Genetic Sequencing in Saudi Patients with Systemic Lupus Erythematosus.Open Access Rheumatol202642770033PubTator, text miningPubMed
Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune-Shielded Heart Valves.Adv Healthc Mater202642765550PubTator, text miningPubMed
Generation of isogenic gene-corrected cell lines from a USH2A-RP patient-derived iPS cell line.Stem Cell Res202642710431PubTator, text miningPubMed
Whole-Exome Sequencing in a Consanguinity-Enriched South Indian Retinitis Pigmentosa Cohort: Diagnostic Yield and Molecular Spectrum.Ophthalmol Sci202642701422PubTator, text miningPubMed
USH2A-Associated Retinitis Pigmentosa in Koreans: Molecular Genetics and Clinical Characteristics.Am J Ophthalmol202642692131PubTator, text miningPubMed
Characterizing the non-pigmented retinitis pigmentosa in a Chinese cohort: Insights into phenotype, genotype, and disease progression.Adv Ophthalmol Pract Res202642668498PubTator, text miningPubMed

1 to 10 of 2,630

See all 2,630 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7399

GET https://conductscience.org/api/genes/v1/7399/patents?page=2