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Gene · 7402

UTRN: utrophin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UTRN: utrophin. Genes, record 7402. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7402

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Gene

Symbol
UTRN
HGNC
Name
utrophin
HGNC
NCBI Gene ID
7402
NCBI Gene
HGNC ID
HGNC:12635
HGNC
Ensembl
ENSG00000152818
NCBI Gene
Aliases
DMDL, DRP, DRP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P46939Utrophin3,4333Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469439P46939Espacenet
EP 4650780 A22025-11-198248P46939Espacenet
EP 4641201 A22025-10-298428P46939Espacenet
EP 4641202 A22025-10-295399P46939Espacenet
JP 2025517969 A2025-06-128428P46939Espacenet
JP 2025517970 A2025-06-128248P46939Espacenet
KR 1020250017231 A2025-02-045399P46939Espacenet
WO 2025017168 A12025-01-231P46939Espacenet
EP 4463571 A12024-11-20267P46939Espacenet
JP 2022141755 A2022-09-29301P46939Espacenet

1 to 10 of 33

See all 33 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
EZUTROMIDCHEMBL1773683Utrophin modulatorMODULATOR

Source ChEMBL

Trials3

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02858362EZUTROMIDPHASE22020-01-02ClinicalTrials.gov
NCT02383511EZUTROMIDPHASE1ClinicalTrials.gov
NCT02056808EZUTROMIDPHASE1ClinicalTrials.gov

NIH grants2,352

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUTRN papersNewest fiscal year
R01AR042423Cytoskeletal Interactions of Dystrophin182025
R01AR040864Dystrophin Replacement92025
P40OD010440Caenorhabditis Genetics Center82025
T32AR007612Minnesota Muscle Training Program82025
ZIANS002859Targeting Protein Aggregates for Autophagosomal Degradation72025
ZIANS003123Role of mitochondria in neurodegenerative diseases72025
P30CA014195Cancer Center Support Grant (CCSG)62025
P30CA016672Cancer Center Support Grant62025
P30CA047904Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025

1 to 10 of 2,352Source NIH's project files

See all 2,352 nih grants

Papers3,966

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Periodontal ligament stem cells ameliorate experimental colitis by restoring macrophage mitochondrial homeostasis associated with PINK1/Parkin-related mitochondrial quality control.Biochim Biophys Acta Mol Basis Dis202742586510PubTator, text miningPubMed
NSD2 drives triple-negative breast cancer progression via ATAD3A-dependent senescence.Cell Signal202642822681PubTator, text miningPubMed
The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms.Mini Rev Med Chem202642817107PubTator, text miningPubMed
Mitochondrial Quality Control: A Gatekeeper of Spermatogenesis.J Vis Exp202642813713PubTator, text miningPubMed
Benzamil-induced cytotoxicity in non-small cell lung cancer is associated with mitochondrial damage, mitochondrial elongation, and altered XIAP signaling.J Pharmacol Sci202642810781PubTator, text miningPubMed
BRET-Based Mitochondrial Subcompartment Localization Biosensors Reveal the Impact of Pesticides and Food Additives on Mitochondrial Protein Localization.ACS Sens202642801737PubTator, text miningPubMed
Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer.Adv Sci (Weinh)202642801628PubTator, text miningPubMed
Uncovering hidden protein networks in Huntington's disease: implications for pathogenesis and therapy.Mol Biol Rep202642801363PubTator, text miningPubMed
iRoot BP Plus Sustains Mitochondrial Homeostasis in Human Dental Pulp Stem Cells Subjected to Oxidative Stress.Aust Endod J202642791642PubTator, text miningPubMed
Actin conformation dynamics precede force generation in cytotoxic T lymphocytes.Commun Biol202642791267PubTator, text miningPubMed

1 to 10 of 3,966

See all 3,966 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7402

GET https://conductscience.org/api/genes/v1/7402/patents?page=2