Gene · 7402
UTRN: utrophin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. UTRN: utrophin. Genes, record 7402. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7402
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P46939 | Utrophin | 3,433 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69439 | P46939 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 8248 | P46939 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8428 | P46939 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5399 | P46939 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8428 | P46939 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 8248 | P46939 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5399 | P46939 | Espacenet |
| WO 2025017168 A1 | 2025-01-23 | 1 | P46939 | Espacenet |
| EP 4463571 A1 | 2024-11-20 | 267 | P46939 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 301 | P46939 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| EZUTROMID | CHEMBL1773683 | Utrophin modulator | MODULATOR |
Source ChEMBL
Trials3
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT02858362 | EZUTROMID | PHASE2 | 2020-01-02 | ClinicalTrials.gov |
| NCT02383511 | EZUTROMID | PHASE1 | ClinicalTrials.gov | |
| NCT02056808 | EZUTROMID | PHASE1 | ClinicalTrials.gov |
NIH grants2,352
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | UTRN papers | Newest fiscal year |
|---|---|---|---|
| R01AR042423 | Cytoskeletal Interactions of Dystrophin | 18 | 2025 |
| R01AR040864 | Dystrophin Replacement | 9 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 8 | 2025 |
| T32AR007612 | Minnesota Muscle Training Program | 8 | 2025 |
| ZIANS002859 | Targeting Protein Aggregates for Autophagosomal Degradation | 7 | 2025 |
| ZIANS003123 | Role of mitochondria in neurodegenerative diseases | 7 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 5 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 5 | 2025 |
1 to 10 of 2,352Source NIH's project files
See all 2,352 nih grantsPapers3,966
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Periodontal ligament stem cells ameliorate experimental colitis by restoring macrophage mitochondrial homeostasis associated with PINK1/Parkin-related mitochondrial quality control. | Biochim Biophys Acta Mol Basis Dis | 2027 | 42586510 | PubTator, text mining | PubMed |
| NSD2 drives triple-negative breast cancer progression via ATAD3A-dependent senescence. | Cell Signal | 2026 | 42822681 | PubTator, text mining | PubMed |
| The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms. | Mini Rev Med Chem | 2026 | 42817107 | PubTator, text mining | PubMed |
| Mitochondrial Quality Control: A Gatekeeper of Spermatogenesis. | J Vis Exp | 2026 | 42813713 | PubTator, text mining | PubMed |
| Benzamil-induced cytotoxicity in non-small cell lung cancer is associated with mitochondrial damage, mitochondrial elongation, and altered XIAP signaling. | J Pharmacol Sci | 2026 | 42810781 | PubTator, text mining | PubMed |
| BRET-Based Mitochondrial Subcompartment Localization Biosensors Reveal the Impact of Pesticides and Food Additives on Mitochondrial Protein Localization. | ACS Sens | 2026 | 42801737 | PubTator, text mining | PubMed |
| Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer. | Adv Sci (Weinh) | 2026 | 42801628 | PubTator, text mining | PubMed |
| Uncovering hidden protein networks in Huntington's disease: implications for pathogenesis and therapy. | Mol Biol Rep | 2026 | 42801363 | PubTator, text mining | PubMed |
| iRoot BP Plus Sustains Mitochondrial Homeostasis in Human Dental Pulp Stem Cells Subjected to Oxidative Stress. | Aust Endod J | 2026 | 42791642 | PubTator, text mining | PubMed |
| Actin conformation dynamics precede force generation in cytotoxic T lymphocytes. | Commun Biol | 2026 | 42791267 | PubTator, text mining | PubMed |
1 to 10 of 3,966
See all 3,966 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7402
GET https://conductscience.org/api/genes/v1/7402/patents?page=2