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Gene · 7405

UVRAG: UV radiation resistance associated

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UVRAG: UV radiation resistance associated. Genes, record 7405. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7405

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Gene

Symbol
UVRAG
HGNC
Name
UV radiation resistance associated
HGNC
NCBI Gene ID
7405
NCBI Gene
HGNC ID
HGNC:12640
HGNC
Ensembl
ENSG00000198382
NCBI Gene
Aliases
DHTX, VPS38, p63
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9P2Y5UV radiation resistance-associated gene protein6993Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469447Q9P2Y5Espacenet
EP 4650780 A22025-11-197252Q9P2Y5Espacenet
JP 2025517970 A2025-06-127252Q9P2Y5Espacenet
JP 2023123507 A2023-09-05360Q9P2Y5Espacenet
US 11446398 B22022-09-2096072Q9P2Y5Espacenet
JP 2022524081 A2022-04-27199043Q9P2Y5Espacenet
US 11078247 B22021-08-0312429Q9P2Y5Espacenet
JP 2020524809 A2020-08-20360Q9P2Y5Espacenet
JP 2019054813 A2019-04-11249882Q9P2Y5Espacenet
WO 2018234577 A12018-12-27360Q9P2Y5Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants992

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUVRAG papersNewest fiscal year
R01CA140964Autophagy-mediated defense against inflammation and cancer182025
R01NS060123Neuronal Autophagy: a Cell-Autonomous Protection Mechanism122025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital102025
P30CA016672Cancer Center Support Grant72025
R35GM131919The mechanism and regulation of autophagy72025
R01CA126792Autophagy and Pro-metastatic Differentiation52025
ZIAHL006151Lysosome biogenesis and homeostasis42025
P30AG028740University of Florida Older Americans Independence Center (OAIC)32025
P30CA021765Cancer Center Support Grant (CCSG)32025
R01DK079879Autophagy in liver injury32025

1 to 10 of 992Source NIH's project files

See all 992 nih grants

Papers1,684

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative Cross-Population Multi-Database Analysis Reveals an Association Between GORASP2 and Autophagy in Glioblastoma.J Pak Med Assoc202642817668PubTator, text miningPubMed
A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution.Elife202642207670PubTator, text miningPubMed
Autophagy-centered gene networks reveal prognostic biomarkers and therapeutic targets in esophageal cancer.Discov Oncol202642204123PubTator, text miningPubMed
Structure-Based Design of UVRAG-BAX Binding Interface-Targeting Compound Induces Apoptosis and ROS in Breast Cancer Cells.Biochemistry202642117566PubTator, text miningPubMed
Two binding sites are better than one.Elife202641919593PubTator, text miningPubMed
Vps16 Attenuates Myocardial Ischemia/reperfusion Injury by Interacting with UVRAG and Activating Rab7.Cardiovasc Drugs Ther202641854796PubTator, text miningPubMed
Intravenous immunoglobulin remodels innate immune cell communication and induces differential autophagy pathways in Kawasaki disease.Front Immunol202641822482PubTator, text miningPubMed
Dual targeting of the UPS and autophagy as a novel therapy for neurodegenerative proteinopathies.Front Cell Neurosci202641788195PubTator, text miningPubMed
Effects of Autophagy Inhibition by SAR405, a Selective VPS34 Inhibitor, on Pleural Mesothelioma Cells.Thorac Cancer202641771171PubTator, text miningPubMed
Identification of multigene predictors of prognosis in patients with ovarian cancer.iScience202641767263PubTator, text miningPubMed

1 to 10 of 1,684

See all 1,684 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7405

GET https://conductscience.org/api/genes/v1/7405/patents