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Gene · 7417

VDAC2: voltage dependent anion channel 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. VDAC2: voltage dependent anion channel 2. Genes, record 7417. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7417

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Gene

Symbol
VDAC2
HGNC
Name
voltage dependent anion channel 2
HGNC
NCBI Gene ID
7417
NCBI Gene
HGNC ID
HGNC:12672
HGNC
Ensembl
ENSG00000165637
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P45880Non-selective voltage-gated ion channel VDAC22943Ensembl, GeneID, HGNC

Source UniProt

Patents52

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469728P45880Espacenet
JP 2026004568 A2026-01-1469733P45880Espacenet
EP 4650780 A22025-11-199132P45880Espacenet
WO 2025181096 A12025-09-042P45880Espacenet
JP 2025517970 A2025-06-129132P45880Espacenet
JP 2023123507 A2023-09-05223P45880Espacenet
US 11708396 B22023-07-252061P45880Espacenet
US 11708396 B22023-07-252066P45880Espacenet
US 11446398 B22022-09-2096841P45880Espacenet
US 11446398 B22022-09-2096844P45880Espacenet

1 to 10 of 52

See all 52 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants881

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleVDAC2 papersNewest fiscal year
P30CA138313Medical University of South Carolina - Cancer Center Support Grant62025
R01GM071779Phosphine-Catalyzed Annulations and their Applications62025
P30CA016672Cancer Center Support Grant52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
P30DK123704MUSC Digestive Disease Research Core Center42025
ZIAHD000072Biophysics of Large Membrane Channels42025
R35GM133552Coordination of chaperone interactions that dictate protein folding and trafficking32025
T32ES018827Research Training in Environmental Toxicology32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P20GM130457COBRE in Digestive and Liver Disease22025

1 to 10 of 881Source NIH's project files

See all 881 nih grants

Papers1,534

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Spatial control of mitochondrial ubiquitination by the AMBRA1-RMC1-HUWE1 axis.Autophagy202642747977PubTator, text miningPubMed
Revealing the Shared Genetic Architecture of Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Traits Through Genomic Structural Equation Modeling.Genet Epidemiol202642701886PubTator, text miningPubMed
Voltage-dependent anion channel 2 (VDAC2) drives rituximab resistance via inhibiting ferroptosis in diffuse large B cell lymphoma.Chin Med J (Engl)202642619379PubTator, text miningPubMed
Erastin-sensitive VDAC2 contributes to time-course peritoneal fibrosis via ferroptosis signaling induction.Mol Cell Biochem202642606682PubTator, text miningPubMed
Arecoline promotes oral submucous fibrosis by enhancing epithelial cell cuproptosis through PUS1-mediated pseudouridylation.3 Biotech202642523757PubTator, text miningPubMed
A visualizable mitochondrial-targeted Chlorambucil prodrug for enhancing anti-hepatoma efficacy.Pharm Sci Adv202642518555PubTator, text miningPubMed
Dibutyl phthalate exposure induced hepatotoxicity via VDAC2 mediated mitochondria-dependent ferroptosis.Aquat Toxicol202642501521PubTator, text miningPubMed
Mitochondrial Voltage-Dependent Anion Channel: From a Passive Pore to a Cellular Hub Through Protein Complexation.Int J Mol Sci202642450075PubTator, text miningPubMed
Survivin Associates with VDAC2 and Bcl2-Family Proteins at the Mitochondrial Outer Membrane.Int J Mol Sci202642449981PubTator, text miningPubMed
Research progress on VDAC2 in mitochondrial dysfunction-related diseases.Mol Biol Rep202642429877PubTator, text miningPubMed

1 to 10 of 1,534

See all 1,534 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7417

GET https://conductscience.org/api/genes/v1/7417/patents?page=2