Gene · 7417
VDAC2: voltage dependent anion channel 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. VDAC2: voltage dependent anion channel 2. Genes, record 7417. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7417
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P45880 | Non-selective voltage-gated ion channel VDAC2 | 294 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents52
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69728 | P45880 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 69733 | P45880 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9132 | P45880 | Espacenet |
| WO 2025181096 A1 | 2025-09-04 | 2 | P45880 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9132 | P45880 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 223 | P45880 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 2061 | P45880 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 2066 | P45880 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 96841 | P45880 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 96844 | P45880 | Espacenet |
1 to 10 of 52
See all 52 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants881
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | VDAC2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 6 | 2025 |
| R01GM071779 | Phosphine-Catalyzed Annulations and their Applications | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 5 | 2025 |
| P30DK123704 | MUSC Digestive Disease Research Core Center | 4 | 2025 |
| ZIAHD000072 | Biophysics of Large Membrane Channels | 4 | 2025 |
| R35GM133552 | Coordination of chaperone interactions that dictate protein folding and trafficking | 3 | 2025 |
| T32ES018827 | Research Training in Environmental Toxicology | 3 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 2 | 2025 |
| P20GM130457 | COBRE in Digestive and Liver Disease | 2 | 2025 |
1 to 10 of 881Source NIH's project files
See all 881 nih grantsPapers1,534
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Spatial control of mitochondrial ubiquitination by the AMBRA1-RMC1-HUWE1 axis. | Autophagy | 2026 | 42747977 | PubTator, text mining | PubMed |
| Revealing the Shared Genetic Architecture of Metabolic Dysfunction-Associated Steatotic Liver Disease-Related Traits Through Genomic Structural Equation Modeling. | Genet Epidemiol | 2026 | 42701886 | PubTator, text mining | PubMed |
| Voltage-dependent anion channel 2 (VDAC2) drives rituximab resistance via inhibiting ferroptosis in diffuse large B cell lymphoma. | Chin Med J (Engl) | 2026 | 42619379 | PubTator, text mining | PubMed |
| Erastin-sensitive VDAC2 contributes to time-course peritoneal fibrosis via ferroptosis signaling induction. | Mol Cell Biochem | 2026 | 42606682 | PubTator, text mining | PubMed |
| Arecoline promotes oral submucous fibrosis by enhancing epithelial cell cuproptosis through PUS1-mediated pseudouridylation. | 3 Biotech | 2026 | 42523757 | PubTator, text mining | PubMed |
| A visualizable mitochondrial-targeted Chlorambucil prodrug for enhancing anti-hepatoma efficacy. | Pharm Sci Adv | 2026 | 42518555 | PubTator, text mining | PubMed |
| Dibutyl phthalate exposure induced hepatotoxicity via VDAC2 mediated mitochondria-dependent ferroptosis. | Aquat Toxicol | 2026 | 42501521 | PubTator, text mining | PubMed |
| Mitochondrial Voltage-Dependent Anion Channel: From a Passive Pore to a Cellular Hub Through Protein Complexation. | Int J Mol Sci | 2026 | 42450075 | PubTator, text mining | PubMed |
| Survivin Associates with VDAC2 and Bcl2-Family Proteins at the Mitochondrial Outer Membrane. | Int J Mol Sci | 2026 | 42449981 | PubTator, text mining | PubMed |
| Research progress on VDAC2 in mitochondrial dysfunction-related diseases. | Mol Biol Rep | 2026 | 42429877 | PubTator, text mining | PubMed |
1 to 10 of 1,534
See all 1,534 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7417
GET https://conductscience.org/api/genes/v1/7417/patents?page=2