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VDR: vitamin D receptor

1 protein, 113 patents, 19 drugs, 866 trials, 7,369 NIH grants and 22,845 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolVDRHGNC
Namevitamin D receptorHGNC
NCBI Gene ID7421NCBI Gene
HGNC IDHGNC:12679HGNC
EnsemblENSG00000111424NCBI Gene
AliasesNR1I1, PPP1R163NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P11473Vitamin D3 receptor42752Ensembl, GeneID, HGNCUniProt

Patents 113

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086503 A2026-05-2679P11473Espacenet
JP 2026004568 A2026-01-1469686P11473Espacenet
JP 2026004568 A2026-01-1469687P11473Espacenet
JP 2026004568 A2026-01-1469691P11473Espacenet
EP 4650780 A22025-11-1911259P11473Espacenet
EP 4641202 A22025-10-2938392P11473Espacenet
EP 4641202 A22025-10-295931P11473Espacenet
JP 2025147176 A2025-10-0615831P11473Espacenet
JP 2025517970 A2025-06-1211259P11473Espacenet
EP 4516308 A22025-03-0579P11473Espacenet

Drugs 19

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALFACALCIDOLCHEMBL1601669Vitamin D receptor agonistAGONISTChEMBL
BECOCALCIDIOLCHEMBL2104955Vitamin D receptor agonistAGONISTChEMBL
CALCIFEDIOLCHEMBL3544909Vitamin D receptor agonistAGONISTChEMBL
CALCIFEDIOL ANHYDROUSCHEMBL1040Vitamin D receptor agonistAGONISTChEMBL
CALCIPOTRIENECHEMBL1200666Vitamin D receptor agonistAGONISTChEMBL
CALCITRIOLCHEMBL846Vitamin D receptor agonistAGONISTChEMBL
CHOLECALCIFEROLCHEMBL1042Vitamin D receptor agonistAGONISTChEMBL
DIHYDROTACHYSTEROLCHEMBL2356023Vitamin D receptor agonistAGONISTChEMBL
DOXERCALCIFEROLCHEMBL1200810Vitamin D receptor agonistAGONISTChEMBL
DP001CHEMBL605525Vitamin D receptor agonistAGONISTChEMBL

Trials 866

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07598032CHOLECALCIFEROLPHASE3ClinicalTrials.gov
NCT07598032ERGOCALCIFEROLPHASE3ClinicalTrials.gov
NCT07553052CHOLECALCIFEROLClinicalTrials.gov
NCT07543926ERGOCALCIFEROLClinicalTrials.gov
NCT07494045CALCIFEDIOLPHASE2ClinicalTrials.gov
NCT07479303CALCIFEDIOLClinicalTrials.gov
NCT07460336CHOLECALCIFEROLClinicalTrials.gov
NCT07458815ERGOCALCIFEROLClinicalTrials.gov
NCT07453472CALCIPOTRIENEPHASE3ClinicalTrials.gov
NCT07410793CALCIPOTRIENEPHASE2ClinicalTrials.gov

NIH grants 7369

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant482,025NIH's project files
R01AR073004Mechanism of action and function of novel secosteroid 20(OH)D3 in the skin362,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant352,025NIH's project files
I01BX004293CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancer322,025NIH's project files
P30CA016672Cancer Center Support Grant292,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)262,025NIH's project files
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)232,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant202,025NIH's project files
R01DK114126How Vitamin D Receptor Influences Intestinal Barriers202,025NIH's project files
P30CA016058Cancer Center Support Grant172,025NIH's project files

Papers 22845

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825856PubTator, text miningPubMed
42824782PubTator, text miningPubMed
42823066PubTator, text miningPubMed
42820997PubTator, text miningPubMed
42818011PubTator, text miningPubMed
42812403PubTator, text miningPubMed
42807304PubTator, text miningPubMed
42801394PubTator, text miningPubMed
42798859PubTator, text miningPubMed
42797461PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license