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VEGFC: vascular endothelial growth factor C

1 protein, 222 patents, 1 drug, 27 trials, 3,870 NIH grants and 10,109 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolVEGFCHGNC
Namevascular endothelial growth factor CHGNC
NCBI Gene ID7424NCBI Gene
HGNC IDHGNC:12682HGNC
EnsemblENSG00000150630NCBI Gene
AliasesFlt4-L, LMPH1D, LMPHM4, VEGF-C, VRPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P49767Vascular endothelial growth factor C4194Ensembl, GeneID, HGNCUniProt

Patents 222

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2025253101 A12025-12-1118P49767Espacenet
EP 4650780 A22025-11-1918465P49767Espacenet
EP 4641201 A22025-10-2922990P49767Espacenet
JP 2025147176 A2025-10-0614053P49767Espacenet
JP 2025529142 A2025-09-048024P49767Espacenet
JP 2025527176 A2025-08-202P49767Espacenet
US 12371689 B22025-07-298024P49767Espacenet
US 12365726 B22025-07-2211P49767Espacenet
JP 2025517969 A2025-06-1222990P49767Espacenet
JP 2025517970 A2025-06-1218465P49767Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CONBERCEPTCHEMBL2108313Vascular endothelial growth factor C inhibitorINHIBITORChEMBL

Trials 27

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07144865CONBERCEPTClinicalTrials.gov
NCT06717412CONBERCEPTClinicalTrials.gov
NCT05728476CONBERCEPTClinicalTrials.gov
NCT05539235CONBERCEPTPHASE2/PHASE3ClinicalTrials.gov
NCT05229237CONBERCEPTClinicalTrials.gov
NCT05222633CONBERCEPTClinicalTrials.gov
NCT04990271CONBERCEPTPHASE2ClinicalTrials.gov
NCT04782115CONBERCEPTPHASE2ClinicalTrials.gov
NCT04627402CONBERCEPTClinicalTrials.gov
NCT04296838CONBERCEPTPHASE2/PHASE3ClinicalTrials.gov

NIH grants 3870

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant432,025NIH's project files
P30CA016672Cancer Center Support Grant402,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award162,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant132,025NIH's project files
T32CA009501Surgical Oncology Research Training Grant122,025NIH's project files
P30EY001792P30 Core Grant for Vision Research112,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase102,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant102,025NIH's project files
P30CA012197Cancer Center Support Grant82,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support82,025NIH's project files

Papers 10109

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821477PubTator, text miningPubMed
42793248PubTator, text miningPubMed
42789144PubTator, text miningPubMed
42781620PubTator, text miningPubMed
42778431PubTator, text miningPubMed
42748219PubTator, text miningPubMed
42746480PubTator, text miningPubMed
42735790PubTator, text miningPubMed
42727460PubTator, text miningPubMed
42717534PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license