Gene · 7453
WARS1: tryptophanyl-tRNA synthetase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. WARS1: tryptophanyl-tRNA synthetase 1. Genes, record 7453. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7453
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P23381 | Tryptophan--tRNA ligase, cytoplasmic | 471 | 13 | Ensembl, GeneID, HGNC |
Source UniProt
Patents118
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 68417 | P23381 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68419 | P23381 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68441 | P23381 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7159 | P23381 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7075 | P23381 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5231 | P23381 | Espacenet |
| JP 2025120083 A | 2025-08-15 | 1 | P23381 | Espacenet |
| KR 1020250101933 A | 2025-07-04 | 2 | P23381 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7075 | P23381 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7159 | P23381 | Espacenet |
1 to 10 of 118
See all 118 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,662
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | WARS1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| R01NS105789 | Understanding GABAA receptor protein folding and misfolding | 9 | 2025 |
| R28AA012725 | Brain Tissue Resource Center for Alcohol Research | 7 | 2025 |
| P30ES017885 | Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) | 5 | 2025 |
| R35GM122528 | Dynamics Of Ligand Gated Ion Channels | 5 | 2025 |
| U54GM104942 | West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 4 | 2025 |
| P60AA011605 | Molecular and Circuit Pathogenesis of Alcohol Use Disorders | 4 | 2025 |
| R01DA047325 | Structure and Function of GABA-A receptors | 4 | 2025 |
1 to 10 of 2,662Source NIH's project files
See all 2,662 nih grantsPapers3,740
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Accurate measurement of longitudinal paramagnetic relaxation enhancement through division after subtraction. | Magn Reson Lett | 2027 | 42534397 | PubTator, text mining | PubMed |
| PRELP-associated transcriptomic remodeling links alternative splicing and immune checkpoint blockade outcome in melanoma. | Front Immunol | 2026 | 42813001 | PubTator, text mining | PubMed |
| Integrative Proteogenomics and Single-Cell Transcriptomics Prioritize Candidate Causal Proteins and Therapeutic Targets in Age-Related Macular Degeneration. | Int J Mol Sci | 2026 | 42794533 | PubTator, text mining | PubMed |
| AMPK γ-Subunit Isoform Switching Governs Temozolomide Resistance and Survival in Glioblastoma. | Cells | 2026 | 42738889 | PubTator, text mining | PubMed |
| COPI Coatomer Regulates Several Steps of HDL Metabolism. | Arterioscler Thromb Vasc Biol | 2026 | 42592650 | PubTator, text mining | PubMed |
| Tissue origins of the plasma proteomic response to glucose ingestion in humans. | Diabetologia | 2026 | 42467085 | PubTator, text mining | PubMed |
| GABAA receptor dysfunction in autism spectrum disorder: molecular mechanisms and therapeutic opportunities. | Front Pharmacol | 2026 | 42338965 | PubTator, text mining | PubMed |
| Structural basis for activation and potentiation in a human α5β3 GABAA receptor. | Nat Commun | 2026 | 42297817 | PubTator, text mining | PubMed |
| Long-Chain S-Acylation Is a Key Modulator During the Macrophage Inflammatory Response. | Mol Cell Proteomics | 2026 | 42269967 | PubTator, text mining | PubMed |
| Plasma proteomic profiles reveal proteins and characteristic patterns associated with hypertension: A prospective cohort study. | J Hypertens | 2026 | 42160135 | PubTator, text mining | PubMed |
1 to 10 of 3,740
See all 3,740 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7453
GET https://conductscience.org/api/genes/v1/7453/patents?page=2