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NSD2: nuclear receptor binding SET domain protein 2
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Gene · 7468

Papers2,351

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,351

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TitleJournalYearPMIDFound bySource
NSD2 drives triple-negative breast cancer progression via ATAD3A-dependent senescence.Cell Signal202642822681PubTator, text miningPubMed
NSD Histone Methyltransferases in Solid Tumors: Biological Functions, Oncogenic Mechanisms and Therapeutic Targeting.Int J Mol Sci202642794546PubTator, text miningPubMed
Degrading NSD2 rewires the myeloma niche.Blood202642783363PubTator, text miningPubMed
Rauch-Steindl syndrome: intrauterine phenotype and diagnostic utility of prenatal exome sequencing.BMJ Case Rep202642754354PubTator, text miningPubMed
Genomic Characterization of ETV6::RUNX1-Positive Childhood B-ALL in a Chinese Cohort: Novel Fusion Partners, Co-Occurring Mutations, and Risk-Stratifying Biomarkers.Pediatr Blood Cancer202642720515PubTator, text miningPubMed
Phenotypes of Hereditary Diseases Associated With Rauch-Steindl Syndrome.Hum Mutat202642694379PubTator, text miningPubMed
Expanding the Molecular Spectrum of Papillary Renal Neoplasm With Reverse Polarity: A Report of Two Cases and a Literature Review.Cureus202642602752PubTator, text miningPubMed
Alternative Splicing in Cyclin-Dependent Kinase 4/6 Inhibitor Resistance in Estrogen Receptor-Positive Breast Cancer.Drug Dev Res202642574086PubTator, text miningPubMed
Degraders of histone lysine methyltransferases: Progress, challenges, and opportunities.Drug Discov Today202642542162PubTator, text miningPubMed
NSD2 is a critical regulator of Erastin-induced ferroptosis in keratinocytes.Free Radic Biol Med202642462913PubTator, text miningPubMed
Overcoming Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma (HNSCC): The Role of Histone Methyltransferase and Demethylase Inhibitors.Cancers (Basel)202642449712PubTator, text miningPubMed
Discovery and biological evaluation of HS13 as a novel covalent ligand targeting the NSD2-PWWP1 domain.Bioorg Med Chem202642442058PubTator, text miningPubMed
Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer.Nature202642380660PubTator, text miningPubMed
NSD2 degradation remediates the oncogenic cistrome in t(4;14) multiple myeloma.Blood202642371798PubTator, text miningPubMed
Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters.J Cardiovasc Aging202642369572PubTator, text miningPubMed
Aryl Aldehyde-Anchored Small Molecules Recruit FBXO22 for Targeted Degradation of NSD2.J Med Chem202642367045PubTator, text miningPubMed
Decoding the Conformational Dynamics and Hyperactivity of Histone H3K36 N-Methyltransferase in Oncogenic Mutations via tICA and Markov State Modeling.bioRxiv202642327166PubTator, text miningPubMed
Correction to "Identification and Functional Analysis of a Novel NSD2 Missense Variant in a Patient With Rauch-Steindl Syndrome".Mol Genet Genomic Med202642289922PubTator, text miningPubMed
How does NSD2 fuel multiple myeloma?Blood202642275120PubTator, text miningPubMed
Case Report: A de novo NSD2 multiple exon deletion variant in a child with Rauch-Steindl syndrome.Front Pediatr202642221011PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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