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Gene · 7472

WNT2: Wnt family member 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. WNT2: Wnt family member 2. Genes, record 7472. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7472

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Gene

Symbol
WNT2
HGNC
Name
Wnt family member 2
HGNC
NCBI Gene ID
7472
NCBI Gene
HGNC ID
HGNC:12780
HGNC
Ensembl
ENSG00000105989
NCBI Gene
Aliases
INT1L1, IRP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P09544Protein Wnt-23600Ensembl, GeneID, HGNC

Source UniProt

Patents48

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469873P09544Espacenet
EP 4650780 A22025-11-192484P09544Espacenet
EP 4641201 A22025-10-292072P09544Espacenet
JP 2025147176 A2025-10-0614302P09544Espacenet
JP 2025529142 A2025-09-048083P09544Espacenet
US 12371689 B22025-07-298083P09544Espacenet
JP 2025517969 A2025-06-122072P09544Espacenet
JP 2025517970 A2025-06-122484P09544Espacenet
JP 2025028160 A2025-02-2814302P09544Espacenet
KR 1020250010750 A2025-01-2114302P09544Espacenet

1 to 10 of 48

See all 48 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,102

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleWNT2 papersNewest fiscal year
ZIAHD001602Regulation Of Intracellular Iron Metabolism212025
ZIAHD008814Mammalian iron-sulfur cluster biogenesis102025
P30CA016672Cancer Center Support Grant92025
R01ES014901Molecular and Cellular Basis of PCB Developmental Neurotoxicity62025
P30CA008748Cancer Center Support Grant52025
P30ES025128Center for Human Health and the Environment (CHHE)52025
R01DK062277Role of Wnt-Beta-catenin in liver development and metabolic zonation52025
P30CA014051Cancer Center Support (Core) Grant42025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
P30CA062203Cancer Center Support Grant42025

1 to 10 of 2,102Source NIH's project files

See all 2,102 nih grants

Papers3,221

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Investigation of Wnt2's Role in Macrophage Polarization and Its Effects on Sepsis.Immunol Invest202642820465PubTator, text miningPubMed
Midazolam Reduces Metabolic Viability and Induces Apoptosis in MIA PaCa-2 Pancreatic Cancer Cells with Selective Transcriptional Modulation of Wnt and Hedgehog Components: A Preliminary In Vitro Study.
Pharmaceuticals (Basel)202642797517PubTator, text miningPubMed
Ferroptosis-neuroinflammation interplay: mechanistic pathways and therapeutic opportunities in central nervous system disorders.Front Aging Neurosci202642755568PubTator, text miningPubMed
FTH1 mRNA-Protein Discordance in Cardiac Ferroptosis: Multilayer Posttranscriptional and Degradative Control.Cardiovasc Ther202642723477PubTator, text miningPubMed
Perioperative von Willebrand Factor and Factor VIII Kinetics in von Willebrand Disease Patients Treated With Different Clotting Factor Concentrates.Haemophilia202642670766PubTator, text miningPubMed
Potentially functional variants of Wnt signaling pathway genes predict risk of primary lung cancer in Chinese Han population.Sci Rep202642660981PubTator, text miningPubMed
Investigation of WNT2, DISC1, and DOCK4 polymorphisms in a Turkish autism spectrum disorder cohort: a case-control and bioinformatics analysis.Mol Biol Rep202642627543PubTator, text miningPubMed
Whole-transcriptome analysis reveals key transcriptional and noncoding RNA regulators of skeletal muscle satellite cell differentiation in quail.Poult Sci202642617273PubTator, text miningPubMed
A lactate-α-ketoglutarate metabolic circuit in tumor-infiltrating regulatory T cells accelerates tumor progression by inducing NK cell senescence.Nat Cancer202642613377PubTator, text miningPubMed
Polyamines buffer labile iron to suppress ferroptosis.Cell202642600612PubTator, text miningPubMed

1 to 10 of 3,221

See all 3,221 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7472

GET https://conductscience.org/api/genes/v1/7472/patents?page=2