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Gene · 7486

Papers3,630

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Werner helicase inhibitor for advanced microsatellite instability solid tumors: a phase 1 trial.Nat Med202642811189PubTator, text miningPubMed
Replication stress in cancer: origins, consequences and therapeutic opportunities.Nat Rev Cancer202642773173PubTator, text miningPubMed
NEAT1_1-encoded microprotein PSNEAT1 drives rDNA transcription via phase separation with WRN.Proc Natl Acad Sci U S A202642771507PubTator, text miningPubMed
Synthetic lethality and context-selective DNA-damage response dependencies: from genetic vulnerability to pharmacological translation.Drug Discov Today202642727625PubTator, text miningPubMed
The1H, 15N and13C backbone resonance assignments of an intrinsically disordered region (124-270) of BRCA1 associated RING domain 1 (BARD1).Biomol NMR Assign202642678585PubTator, text miningPubMed
Evolutionary study of oncogenes and tumor suppressor genes in breast carcinoma.J Taibah Univ Med Sci202642633313PubTator, text miningPubMed
Werner Syndrome Masquerading as Type 2 Diabetes: A Diagnostic Odyssey Leading to Precision Medicine.Am J Case Rep202642629965PubTator, text miningPubMed
Engineering bubble structures as Cas12a activators for highly sensitive monitoring of WRN helicase function.Biosens Bioelectron202642612455PubTator, text miningPubMed
[WRN and Other RecQ Helicases in Life Cycles of Viruses].Mol Biol (Mosk)202642599232PubTator, text miningPubMed
Potential advantage of clinical exome sequencing in BRCA1/2-negative families: a retrospective study of a cohort of 500 patients at a high-risk for hereditary cancers.J Med Genet202642498519PubTator, text miningPubMed
CRISPR Screening Identifies SMARCAL1 and MRN as Modulators of WRN Dependency in MSI-H Colorectal Cancer.Cancer Res202642484294PubTator, text miningPubMed
Mapping Non-Homologous Pocket Compatibilities to Identify Hidden Drug-Target Relationships: A Pocket Hopping Framework.J Med Chem202642470361PubTator, text miningPubMed
Targeting WRN Helicase in Microsatellite-Instable Colorectal Cancer Induces Antitumor Immunity through Extrachromosomal Circular DNA Release.Cancer Res202642461083PubTator, text miningPubMed
eIF4E2 deficiency translationally unleashes WRN to sustain DNA repair-mediated chemoresistance.Cell Rep202642441405PubTator, text miningPubMed
Effect of WRN helicase on the development and maturation of goat oocytes.Theriogenology202642424899PubTator, text miningPubMed
RecQ DNA helicases germline variants in Lynch-like syndrome.Genet Med Open202642293362PubTator, text miningPubMed
Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors.J Med Chem202642234810PubTator, text miningPubMed
Novel Synthetic Lethal Therapeutic Strategies in Precision Oncology.Am Soc Clin Oncol Educ Book202642207998PubTator, text miningPubMed
Structural basis of Ku-mediated activation of WRN exonuclease activity.Nat Commun202642129166PubTator, text miningPubMed
A mutational scar-based genome-wide map of DNA double-strand break repair.Nat Commun202642103732PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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