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WT1: WT1 transcription factor

1 protein, 312 patents, 2 drugs, 13 trials, 5,579 NIH grants and 16,905 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolWT1HGNC
NameWT1 transcription factorHGNC
NCBI Gene ID7490NCBI Gene
HGNC IDHGNC:12796HGNC
EnsemblENSG00000184937NCBI Gene
AliasesAWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P19544Wilms tumor protein44927Ensembl, GeneID, HGNCUniProt

Patents 312

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026053495 A2026-03-25199P19544Espacenet
JP 2026012826 A2026-01-271P19544Espacenet
JP 2025147176 A2025-10-0615839P19544Espacenet
EP 4609202 A22025-09-032P19544Espacenet
JP 2025106246 A2025-07-15199P19544Espacenet
JP 2025508834 A2025-04-1022P19544Espacenet
JP 2025028160 A2025-02-2815839P19544Espacenet
EP 4494652 A22025-01-2276457P19544Espacenet
KR 1020250010750 A2025-01-2115839P19544Espacenet
EP 4487869 A22025-01-08502P19544Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
GALINPEPIMUT-SCHEMBL3833386Wilms tumor protein vaccine antigenVACCINE ANTIGENChEMBL
OMBIPEPIMUT-SCHEMBL4297235Wilms tumor protein vaccine antigenVACCINE ANTIGENChEMBL

Trials 13

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05593185GALINPEPIMUT-SClinicalTrials.gov
NCT05320809GALINPEPIMUT-SPHASE1ClinicalTrials.gov
NCT04747002OMBIPEPIMUT-SPHASE2ClinicalTrials.gov
NCT04229979GALINPEPIMUT-SPHASE3ClinicalTrials.gov
NCT04040231GALINPEPIMUT-SPHASE1ClinicalTrials.gov
NCT03761914GALINPEPIMUT-SPHASE1/PHASE22024-11-19ClinicalTrials.gov
NCT03311334OMBIPEPIMUT-SPHASE1/PHASE22024-04-18ClinicalTrials.gov
NCT03149003OMBIPEPIMUT-SPHASE32023-01-30ClinicalTrials.gov
NCT02750891OMBIPEPIMUT-SPHASE1/PHASE2ClinicalTrials.gov
NCT02498665OMBIPEPIMUT-SPHASE1ClinicalTrials.gov

NIH grants 5579

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2532,025NIH's project files
P30CA016672Cancer Center Support Grant1812,025NIH's project files
P30CA016058Cancer Center Support Grant522,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)472,025NIH's project files
U10CA180899Children's Oncology Group Statistics and Data Center402,025NIH's project files
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement372,025NIH's project files
P01CA018029Adult Leukemia Research Center332,025NIH's project files
P30CA006973Regional Oncology Research Center282,025NIH's project files
P50CA217694SPORE in Soft Tissue Sarcoma252,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant232,025NIH's project files

Papers 16905

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825054PubTator, text miningPubMed
42824020PubTator, text miningPubMed
42821569PubTator, text miningPubMed
42821141PubTator, text miningPubMed
42802991PubTator, text miningPubMed
42802427PubTator, text miningPubMed
42801529PubTator, text miningPubMed
42794413PubTator, text miningPubMed
42791104PubTator, text miningPubMed
42788146PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license