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XPO1: exportin 1

1 protein, 56 patents, 1 drug, 176 trials, 3,721 NIH grants and 6,862 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolXPO1HGNC
Nameexportin 1HGNC
NCBI Gene ID7514NCBI Gene
HGNC IDHGNC:12825HGNC
EnsemblENSG00000082898NCBI Gene
AliasesCRM-1, CRM1, emb, exp1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O14980Exportin-11,07118Ensembl, GeneID, HGNCUniProt

Patents 56

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445652O14980Espacenet
JP 2026004568 A2026-01-1445653O14980Espacenet
JP 2026004568 A2026-01-1445654O14980Espacenet
EP 4650780 A22025-11-1911860O14980Espacenet
EP 4641201 A22025-10-2912650O14980Espacenet
JP 2025517969 A2025-06-1212650O14980Espacenet
JP 2025517970 A2025-06-1211860O14980Espacenet
WO 2024240908 A12024-11-2832O14980Espacenet
US 11845958 B22023-12-199O14980Espacenet
US 11446398 B22022-09-2029195O14980Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
SELINEXORCHEMBL3545185Exportin-1 inhibitorINHIBITORChEMBL

Trials 176

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07569757SELINEXORPHASE3ClinicalTrials.gov
NCT07523737SELINEXORPHASE2ClinicalTrials.gov
NCT07514052SELINEXORClinicalTrials.gov
NCT07479979SELINEXORPHASE1/PHASE2ClinicalTrials.gov
NCT07447817SELINEXORPHASE2ClinicalTrials.gov
NCT07437170SELINEXORPHASE2ClinicalTrials.gov
NCT07405255SELINEXORPHASE2ClinicalTrials.gov
NCT07236931SELINEXORClinicalTrials.gov
NCT07204041SELINEXORPHASE2ClinicalTrials.gov
NCT07200102SELINEXORPHASE1ClinicalTrials.gov

NIH grants 3721

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant612,025NIH's project files
P30CA008748Cancer Center Support Grant482,025NIH's project files
P30CA016058Cancer Center Support Grant312,025NIH's project files
R01CA080728Oncogenic Impact of eIF4E-dependent RNA Export in Cancer152,025NIH's project files
R01CA098571Molecular Mechanisms of eIF4E Mediated Transformation142,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)122,025NIH's project files
R01AI110221The Cell Biology of HIV-1 Genome Trafficking112,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant92,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant92,025NIH's project files
P30CA022453CANCER CENTER SUPPORT GRANT82,025NIH's project files

Papers 6862

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823448PubTator, text miningPubMed
42811544PubTator, text miningPubMed
42798230PubTator, text miningPubMed
42793104PubTator, text miningPubMed
42784657PubTator, text miningPubMed
42782796PubTator, text miningPubMed
42775025PubTator, text miningPubMed
42757385PubTator, text miningPubMed
42732352PubTator, text miningPubMed
42689336PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license