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XRCC4: X-ray repair cross complementing 4
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Gene · 7518

Papers3,098

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 3,098

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TitleJournalYearPMIDFound bySource
Cellular effects of silver diamine fluoride in oral cells.J Oral Biosci202642822289PubTator, text miningPubMed
Non-syndromic premature ovarian insufficiency associated with monoallelic LIG4 mutation via haploinsufficiency.J Ovarian Res202642343416PubTator, text miningPubMed
Systematic discovery of UFM1 receptors reveals a regulatory module in DNA repair directing non-homologous end-joining.Nat Commun202642297806PubTator, text miningPubMed
Evaluation of XRCC4 and VEGF Gene Variants in Relation to Breast Cancer Risk in a Jordanian Cohort.Cancer Manag Res202642255530PubTator, text miningPubMed
Lesions initiating spontaneous mitotic crossover are minimally subject to non-homologous end joining.bioRxiv202642182344PubTator, text miningPubMed
Genome-wide mapping of Cas9-induced sister chromatid exchange across single and over 200 genomic targets.bioRxiv202642182287PubTator, text miningPubMed
Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities.J Biomed Sci202641928257PubTator, text miningPubMed
TDP-43 related amyotrophic lateral sclerosis-frontotemporal dementia and links to the DNA damage response: a systematic review and narrative synthesis.Front Mol Neurosci202641924615PubTator, text miningPubMed
An Update on Inborn Errors of V(D)J Recombination.Physiology (Bethesda)202641902554PubTator, text miningPubMed
Nonhomologous end joining-the importance of end tethering and beyond.Genes Dev202641871908PubTator, text miningPubMed
Finely-tuned regulator of DNA repair: FBXW7-185aa may modulate glioblastoma radiosensitization and the tumor immune microenvironment.Transl Oncol202641861660PubTator, text miningPubMed
IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis.Oncogenesis202641844580PubTator, text miningPubMed
Ultraviolet A plays a protective role in ultraviolet B-induced squamous cell carcinoma through c-Fos/XRCC4 axis.Carcinogenesis202641818715PubTator, text miningPubMed
Targeting the Non-Homologous End Joining Pathway Sensitizes MDM2-Amplified Liposarcoma to Doxorubicin by Enhancing p53-Mediated Senescence.Cancer Res202641811692PubTator, text miningPubMed
FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-Oxide.MedComm (2020)202641799933PubTator, text miningPubMed
Next Generation DNA Damage Response Inhibitors: Harnessing Nanocarriers and Tumor Microenvironment for Precision Cancer Therapy.Oncol Res202641799521PubTator, text miningPubMed
Caffeine inhibits nonhomologous end joining by impairing ligase IV/XRCC4 function.Nucleic Acids Res202641773020PubTator, text miningPubMed
Zinc finger proteins (ZFPs) in health and disease.Mol Biomed202641772312PubTator, text miningPubMed
Dysregulation of the DNA damage response by phosphorothioate antisense oligonucleotides.Nat Commun202641760661PubTator, text miningPubMed
Controlling Biogenesis and Engineering of Exosomes to Inhibit Growth and Promote Death in Glioblastoma Multiforme.Brain Sci202641750131PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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