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XRCC5: X-ray repair cross complementing 5

1 protein, 89 patents, 0 drugs, 0 trials, 3,684 NIH grants and 6,144 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolXRCC5HGNC
NameX-ray repair cross complementing 5HGNC
NCBI Gene ID7520NCBI Gene
HGNC IDHGNC:12833HGNC
EnsemblENSG00000079246NCBI Gene
AliasesKARP-1, KARP1, KU80, KUB2, Ku86, NFIVNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P13010DNA repair protein Ku8073264Ensembl, GeneID, HGNCUniProt

Patents 89

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910895P13010Espacenet
EP 4641201 A22025-10-2911271P13010Espacenet
JP 2025517969 A2025-06-1211271P13010Espacenet
JP 2025517970 A2025-06-1210895P13010Espacenet
EP 4464338 A22024-11-20280P13010Espacenet
JP 2024123008 A2024-09-109143P13010Espacenet
JP 2024123008 A2024-09-109144P13010Espacenet
US 11879000 B22024-01-2310P13010Espacenet
US 11860162 B22024-01-021078P13010Espacenet
JP 2023123507 A2023-09-0531P13010Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3684

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA092584Structural Cell Biology of DNA Repair Machines792,025NIH's project files
P30CA016672Cancer Center Support Grant422,025NIH's project files
P30CA008748Cancer Center Support Grant372,025NIH's project files
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center132,025NIH's project files
ZIAAG000726Function of RecQ helicases in genome stability132,025NIH's project files
P30CA056036Translational Research in Cancer122,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)102,025NIH's project files
P30CA033572Cancer Center Support Grant102,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA102,025NIH's project files
R01AI020047Mechanisms That Control Antigen Receptor Variable Region Exon Assembly102,025NIH's project files

Papers 6144

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42815815PubTator, text miningPubMed
42783699PubTator, text miningPubMed
42734342PubTator, text miningPubMed
42585842PubTator, text miningPubMed
42463049PubTator, text miningPubMed
42448921PubTator, text miningPubMed
42442654PubTator, text miningPubMed
42439634PubTator, text miningPubMed
42403051PubTator, text miningPubMed
42399387PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license