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Gene · 7529

YWHAB: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. YWHAB: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta. Genes, record 7529. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7529

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Gene

Symbol
YWHAB
HGNC
Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
HGNC
NCBI Gene ID
7529
NCBI Gene
HGNC ID
HGNC:12849
HGNC
Ensembl
ENSG00000166913
NCBI Gene
Aliases
GW128, HEL-S-1, HS1, KCIP-1, YWHAA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P3194614-3-3 protein beta/alpha24617Ensembl, GeneID, HGNC

Source UniProt

Patents83

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4805736 A22026-09-165P31946Espacenet
JP 2026004568 A2026-01-1468771P31946Espacenet
JP 2026004568 A2026-01-1468772P31946Espacenet
EP 4650780 A22025-11-193989P31946Espacenet
JP 2025147176 A2025-10-0616520P31946Espacenet
JP 2025517970 A2025-06-123989P31946Espacenet
US 12275779 B22025-04-1536P31946Espacenet
JP 2025028160 A2025-02-2816520P31946Espacenet
KR 1020250010750 A2025-01-2116520P31946Espacenet
JP 2024109657 A2024-08-1416359P31946Espacenet

1 to 10 of 83

See all 83 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,103

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleYWHAB papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
R01GM094231COMPUTATIONAL TOOLS FOR MASS SPECTROMETRY-BASED INTERACTOME DATA42025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study32025
P30AG066444Alzheimer's Disease Research Center32025
P30AG066515Stanford Alzheimer's Disease Research Center32025
P30CA014051Cancer Center Support (Core) Grant32025
U19AG032438Bridge Funding for Dominantly Inherited Alzheimer Network32025
P30AG066511Goizueta Alzheimer's Disease Research Center22025

1 to 10 of 1,103Source NIH's project files

See all 1,103 nih grants

Papers1,304

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Isoform-resolved 14-3-3/YWHA networks in colorectal cancer: phospho-adaptor mechanisms, biomarker contexts and therapeutic opportunities.Front Oncol202642688965PubTator, text miningPubMed
Integrated single-cell and experimental validation links effector chondrocyte-associated oxidative stress to EIF6-related p47phox-NOX2 signaling in osteoarthritis.Front Physiol202642630363PubTator, text miningPubMed
From prediction to mechanism: Explainable AI uncovers plasma and CSF proteomic signatures of Alzheimer's disease.J Proteomics202642297098PubTator, text miningPubMed
Clinical significance of serum levels of 14-3-3β protein in patients with non-small cell lung cancer.Sci Rep202642289490PubTator, text miningPubMed
Proteomic Analysis of Cerebrospinal Fluid from Severe COVID-19 Patients Reveals Prognostic Biomarkers Associated with Disease Outcome.Proteomics Clin Appl202641830303PubTator, text miningPubMed
Genetic Evidence Reveals Causal Effect of Circulating Proteome on Random Glucose: A Mendelian Randomization Study.J Diabetes Res202641789253PubTator, text miningPubMed
Genetics and Epigenetics of Obsessive-Compulsive Disorder.Genes (Basel)202641751572PubTator, text miningPubMed
Clinical Spectrum of Cutaneous, Ocular, and Hair Manifestations in Patients With Inborn Errors of Immunity: Insights From a Single Center in Turkey.Immun Inflamm Dis202641738375PubTator, text miningPubMed
Neural - adipose crosstalk: Shared genetic architecture of visceral fat and neuropsychiatric disorders.J Adv Res202641638633PubTator, text miningPubMed
Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition.Commun Biol202641606085PubTator, text miningPubMed

1 to 10 of 1,304

See all 1,304 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7529

GET https://conductscience.org/api/genes/v1/7529/patents?page=2