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Gene · 7536

SF1: splicing factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SF1: splicing factor 1. Genes, record 7536. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7536

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Gene

Symbol
SF1
HGNC
Name
splicing factor 1
HGNC
NCBI Gene ID
7536
NCBI Gene
HGNC ID
HGNC:12950
HGNC
Ensembl
ENSG00000168066
NCBI Gene
Aliases
BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15637Splicing factor 163910Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465324Q15637Espacenet
EP 4650780 A22025-11-199913Q15637Espacenet
EP 4641201 A22025-10-2910186Q15637Espacenet
JP 2025517969 A2025-06-1210186Q15637Espacenet
JP 2025517970 A2025-06-129913Q15637Espacenet
US 11446398 B22022-09-2083594Q15637Espacenet
JP 2022524081 A2022-04-27186565Q15637Espacenet
WO 2020043864 A12020-03-052348Q15637Espacenet
JP 2019054813 A2019-04-11245759Q15637Espacenet
JP 2017121241 A2017-07-13245759Q15637Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,987

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSF1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant262025
R01DK062027Mechanisms of Adrenal Differentiation202025
R01GM070503Molecular Recognition During Pre-mRNA Splicing192025
P30CA016058Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant82025
R01DK043140Mechanisms Leading to Adrenal Zonation82025
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability82025
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension72025
U10CA180882Alliance Statistics and Data Management Center72025
U24CA196171The Alliance NCTN Biorepository and Biospecimen Resource72025

1 to 10 of 1,987Source NIH's project files

See all 1,987 nih grants

Papers3,747

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ZNFX1, an immunoregulatory RNA helicase and E3 ubiquitin ligase, assembles into pleiomorphic polymers.Mol Cell202642822417PubTator, text miningPubMed
The Rare Case of a Sertoli Cell Tumor of the Adrenal Gland in a Man With Pathological Dexamethasone Suppression Test: A Case Report.Cureus202642801029PubTator, text miningPubMed
Alternative splicing remodeling and splicing factor regulatory networks define immune-associated molecular heterogeneity in dilated cardiomyopathy.Front Bioinform202642761222PubTator, text miningPubMed
ALK Expression Without ALK Rearrangement in EWSR1::ATF1-Fused Inflammatory and Nested Testicular Sex Cord Tumor.Diagnostics (Basel)202642739277PubTator, text miningPubMed
Deep Learning Based on Magnetic Resonance Imaging for Preoperative Prediction of Pituitary Neuroendocrine Tumors Subtypes.Acad Radiol202642736093PubTator, text miningPubMed
Human and mouse adrenal glands are characterized by species-specific steroidogenic states and tissue turnover.Nat Genet202642711427PubTator, text miningPubMed
Discovery of the order 'Quisvirales' redefines the evolution of RNA replication and transcription in the phylum Pisuviricota.Virus Evol202642707893PubTator, text miningPubMed
What do you mean by PitNETs in WHO Classification 2022?Endocr J202642702553PubTator, text miningPubMed
Association between preoperative MRI radiomic features and methylation-defined phenotypes in non-functioning pituitary adenomas.Pituitary202642671655PubTator, text miningPubMed
Integrin αvβ6 Expression in the Human Pituitary Gland and Pituitary Neuroendocrine Tumors: Immunohistochemical Characterization with Potential Relevance to αvβ6 PET/CT Pituitary Uptake and Theranostic Implications.
Biomolecules202642650848PubTator, text miningPubMed

1 to 10 of 3,747

See all 3,747 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7536

GET https://conductscience.org/api/genes/v1/7536/patents?page=2