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CA9: carbonic anhydrase 9

1 protein, 142 patents, 6 drugs, 6 trials, 2,679 NIH grants and 8,616 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCA9HGNC
Namecarbonic anhydrase 9HGNC
NCBI Gene ID768NCBI Gene
HGNC IDHGNC:1383HGNC
EnsemblENSG00000107159NCBI Gene
AliasesCAIX, MNNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q16790Carbonic anhydrase 945932Ensembl, GeneID, HGNCUniProt

Patents 142

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026507228 A2026-02-271Q16790Espacenet
WO 2026013158 A12026-01-15416Q16790Espacenet
KR 1020250158048 A2025-11-051Q16790Espacenet
EP 4641201 A22025-10-2910311Q16790Espacenet
JP 2025147176 A2025-10-061953Q16790Espacenet
JP 2025529142 A2025-09-04682Q16790Espacenet
JP 2025529142 A2025-09-045707Q16790Espacenet
US 12371689 B22025-07-295707Q16790Espacenet
US 12371689 B22025-07-29682Q16790Espacenet
JP 2025517969 A2025-06-1210311Q16790Espacenet

Drugs 6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CG250 111INCHEMBL3707280Carbonic anhydrase IX binding agentBINDING AGENTChEMBL
CG250 177LUCHEMBL3707297Carbonic anhydrase IX binding agentBINDING AGENTChEMBL
ETHOXZOLAMIDECHEMBL18Carbonic anhydrase inhibitorINHIBITORChEMBL
GIRENTUXIMABCHEMBL1743027Carbonic anhydrase IX otherOTHERChEMBL
IODINE I 124 GIRENTUXIMABCHEMBL2108713Carbonic anhydrase IX binding agentBINDING AGENTChEMBL
SULTHIAMECHEMBL328560Carbonic anhydrase inhibitorINHIBITORChEMBL

Trials 6

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05885646SULTHIAMEClinicalTrials.gov
NCT05663710GIRENTUXIMABPHASE1/PHASE2ClinicalTrials.gov
NCT05239533GIRENTUXIMABPHASE2ClinicalTrials.gov
NCT05236842SULTHIAMEPHASE2ClinicalTrials.gov
NCT02002312GIRENTUXIMABPHASE2ClinicalTrials.gov
NCT00087022GIRENTUXIMABPHASE32018-09-12ClinicalTrials.gov

NIH grants 2679

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant902,025NIH's project files
P30CA016672Cancer Center Support Grant492,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant242,025NIH's project files
P50CA101942DF/HCC Kidney Cancer SPORE (supplement)212,025NIH's project files
P30CA006973Regional Oncology Research Center182,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant142,025NIH's project files
P30CA006516Dana-Farber/Harvard Cancer Center112,025NIH's project files
R01CA198887MULTIPLEXED PROTEIN BIOMARKER-BASED ASSAY FOR THE DETECTION OF BLADDER CANCER112,025NIH's project files
P30CA016087Cancer Center Support Grant92,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant92,025NIH's project files

Papers 8616

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824820PubTator, text miningPubMed
42823864PubTator, text miningPubMed
42823600PubTator, text miningPubMed
42813978PubTator, text miningPubMed
42808395PubTator, text miningPubMed
42793031PubTator, text miningPubMed
42781707PubTator, text miningPubMed
42779534PubTator, text miningPubMed
42754347PubTator, text miningPubMed
42751052PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license