Gene · 7706
TRIM25: tripartite motif containing 25
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TRIM25: tripartite motif containing 25. Genes, record 7706. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7706
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | 630 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents30
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 68000 | Q14258 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68001 | Q14258 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5523 | Q14258 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5523 | Q14258 | Espacenet |
| JP 2024161501 A | 2024-11-19 | 50 | Q14258 | Espacenet |
| KR 1020240108531 A | 2024-07-09 | 50 | Q14258 | Espacenet |
| US 11542500 B2 | 2023-01-03 | 50 | Q14258 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 92348 | Q14258 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 92349 | Q14258 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 195319 | Q14258 | Espacenet |
1 to 10 of 30
See all 30 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,417
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TRIM25 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P01CA019014 | Viral Oncogenesis, Latency, and Replication | 5 | 2025 |
| P01CA116087 | H. pylori-induced Inflammation and Gastric Cancer | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01AI158704 | Functional analysis of host and viral determinants for ZAP inhibition | 5 | 2025 |
| R37AI087846 | Regulation of Host Innate Immunity Against Viral Infection | 5 | 2025 |
| T32AI060549 | Biodefense Training Program | 5 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 4 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 4 | 2025 |
| ZIAHD001310 | Gene Regulation In The Immune System | 4 | 2025 |
1 to 10 of 1,417Source NIH's project files
See all 1,417 nih grantsPapers2,924
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The response mechanism of mandarin fish (Siniperca chuatsi) astrocyte-like cells to SCRV infection: Insights from Transcriptome Sequencing. | Fish Shellfish Immunol | 2026 | 42815866 | PubTator, text mining | PubMed |
| KAT5-mediated HSPA1A lactylation drives immunotherapy resistance by inhibiting STAT1 degradation in esophageal squamous cell carcinoma. | Oncogene | 2026 | 42786271 | PubTator, text mining | PubMed |
| Integrated bioinformatics analysis, machine learning, and experimental validation reveal that ACSL1 drives myocardial ischemia reperfusion injury via ferroptosis. | J Bioenerg Biomembr | 2026 | 42782425 | PubTator, text mining | PubMed |
| Single-cell profiling reveals context-dependent immune regulation shared by sepsis and systemic lupus erythematosus. | Front Immunol | 2026 | 42755868 | PubTator, text mining | PubMed |
| Guanylate-binding protein 2 (GBP2) drives pancreatic cancer cell proliferation by promoting cell cycle progression via the SP1/SKP2/P27 axis. | J Transl Med | 2026 | 42750038 | PubTator, text mining | PubMed |
| Splenic transcriptomic profiling reveals innate immune responses and RIG-I-like receptor signaling in goslings infected with goose astrovirus. | Front Vet Sci | 2026 | 42718786 | PubTator, text mining | PubMed |
| The TUBA1B-G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression. | Adv Sci (Weinh) | 2026 | 42702897 | PubTator, text mining | PubMed |
| TRIM25 facilitates mitochondrial dysfunction and extracellular matrix degradation by enhancing USP7-driven ENO1 deubiquitination during intervertebral disc degeneration. | Clin Transl Med | 2026 | 42671335 | PubTator, text mining | PubMed |
| LncRNA-miRNA-mRNA Regulatory Network Reveals Potential Immune Responses in Larval Tomato Hind (Cephalopholis sonnerati) Infected with RGNNV. | Biology (Basel) | 2026 | 42651684 | PubTator, text mining | PubMed |
| EF-P-Mediated Enhancement of Protein Synthesis: Cyclic Dipeptide Incorporation Using Mono- and Bisaminoacylated tRNAs. | ACS Chem Biol | 2026 | 42617067 | PubTator, text mining | PubMed |
1 to 10 of 2,924
See all 2,924 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7706
GET https://conductscience.org/api/genes/v1/7706/patents?page=2