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Gene · 778

CACNA1F: calcium voltage-gated channel subunit alpha1 F

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CACNA1F: calcium voltage-gated channel subunit alpha1 F. Genes, record 778. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/778

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Gene

Symbol
CACNA1F
HGNC
Name
calcium voltage-gated channel subunit alpha1 F
HGNC
NCBI Gene ID
778
NCBI Gene
HGNC ID
HGNC:1393
HGNC
Ensembl
ENSG00000102001
NCBI Gene
Aliases
AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60840Voltage-dependent L-type calcium channel subunit alpha-1F1,9770Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19307O60840Espacenet
JP 2026004568 A2026-01-1439648O60840Espacenet
EP 4641201 A22025-10-2910009O60840Espacenet
JP 2025529142 A2025-09-04692O60840Espacenet
US 12371689 B22025-07-29692O60840Espacenet
JP 2025517969 A2025-06-1210009O60840Espacenet
JP 2025062604 A2025-04-1410756O60840Espacenet
JP 2025510310 A2025-04-144O60840Espacenet
US 12246072 B22025-03-1113O60840Espacenet
KR 1020240163152 A2024-11-184O60840Espacenet

1 to 10 of 28

See all 28 patents

Drugs45

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMLODIPINECHEMBL1491Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
AMLODIPINE BENZOATECHEMBL4594262Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
AMLODIPINE BESYLATECHEMBL1200402Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
AMLODIPINE MALEATECHEMBL1200984Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
ATAGABALINCHEMBL593430Voltage-gated calcium channel modulatorMODULATORChEMBL
AZD1305CHEMBL3545169Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
AZELNIDIPINECHEMBL1275868Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
BARNIDIPINECHEMBL2103761Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
BENIDIPINECHEMBL2074972Voltage-gated L-type calcium channel blockerBLOCKERChEMBL
BEPRIDILCHEMBL1008Voltage-gated calcium channel blockerBLOCKERChEMBL

1 to 10 of 45

See all 45 drugs

Trials965

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants484

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCACNA1F papersNewest fiscal year
R01EY026817Calcium channels in retinal photoreceptors112025
P30EY001730Vision Research Core62025
P30CA013696Cancer Center Support Grant32025
R01EY017607Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae32025
R01EY018571Genetics of early onset retinal diseases32025
R01HL121253L-type channel trafficking and modulation in heart32025
R01NS055251Voltage-Gated Calcium Channels in Nociceptors and Mechanoreceptors32025
T32NS007421Neuroscience Training Program32025
P30EY000331Vision Research Core at UCLA22025
P30EY001583P30 Core Grant For Vision Research22025

1 to 10 of 484Source NIH's project files

See all 484 nih grants

Papers843

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Targeting Lung Cancer Stem Cells with Trimebutine: Synergistic Antitumor Activity in Combination with Cisplatin.Int J Mol Sci202642794641PubTator, text miningPubMed
AAV-mediated age- and circuit-dependent restoration of photoreceptor synaptic structure and function in α2δ4-associated retinal synaptopathy.bioRxiv202642539265PubTator, text miningPubMed
Diagnostic discovery of structural variants causing foveal hypoplasia using SVRare and long-read nanopore sequencing.Eur J Hum Genet202642477408PubTator, text miningPubMed
Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy.Clin Genet202642363686PubTator, text miningPubMed
Genetic and Clinical Heterogeneity of Polish Patients with Congenital Stationary Night Blindness (CSNB).Int J Mol Sci202642278384PubTator, text miningPubMed
Genotype-phenotype correlations in Chinese patients with congenital stationary night blindness and early-onset high myopia: evidence from electrophysiology and whole-exome sequencing.Int J Ophthalmol202642211199PubTator, text miningPubMed
Expanding the Genotypic Landscape of Congenital Stationary Night Blindness in an Ethnically Diverse Canadian Population.Hum Mutat202642147812PubTator, text miningPubMed
Electronegative electroretinography in inherited retinal disease: a systematic review of genotype-phenotype correlations.BMC Ophthalmol202642106701PubTator, text miningPubMed
Mutation Screening of ARR3, CACNA1F, P4HA2, TRPM1, COL2A1, COL11A1 and PAX6 in a Chinese Cohort of 37 Patients with Early-Onset High Myopia.Genes (Basel)202642074509PubTator, text miningPubMed
L-type calcium channel-mediated lipid metabolic reprogramming in gastric adenocarcinoma progression.Transl Oncol202641861661PubTator, text miningPubMed

1 to 10 of 843

See all 843 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/778

GET https://conductscience.org/api/genes/v1/778/patents?page=2