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Gene · 7791

ZYX: zyxin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ZYX: zyxin. Genes, record 7791. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7791

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Gene

Symbol
ZYX
HGNC
Name
zyxin
HGNC
NCBI Gene ID
7791
NCBI Gene
HGNC ID
HGNC:13200
HGNC
Ensembl
ENSG00000159840
NCBI Gene
Aliases
ESP-2, HED-2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15942Zyxin5720Ensembl, GeneID, HGNC

Source UniProt

Patents62

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1471001Q15942Espacenet
EP 4650780 A22025-11-195551Q15942Espacenet
EP 4640849 A22025-10-29788Q15942Espacenet
EP 4641201 A22025-10-295173Q15942Espacenet
JP 2025519096 A2025-06-24788Q15942Espacenet
JP 2025517969 A2025-06-125173Q15942Espacenet
JP 2025517970 A2025-06-125551Q15942Espacenet
JP 2025032204 A2025-03-1138637Q15942Espacenet
EP 4461818 A22024-11-1338637Q15942Espacenet
EP 4373841 A12024-05-2959Q15942Espacenet

1 to 10 of 62

See all 62 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,264

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleZYX papersNewest fiscal year
P30CA042014Cancer Center Support Grant152025
ZIAHL005105Integration of Actin Dynamics and Adhesion in Cell Migration92025
R01EY013322Assessment of Corneal Fibroblast Biomechanical Behavior82025
ZIAHL005104Cell Migration in 3D microenvironments72025
P30CA016672Cancer Center Support Grant52025
P30CA036727Buffett Cancer Center Support Grant52025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology42025
R35GM118096Regulating cell fate and shaping the body plan during morphogenesis and their alteration during oncogenesis42025
ZIADE000524Cell-Matrix Interactions and Migration42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025

1 to 10 of 1,264Source NIH's project files

See all 1,264 nih grants

Papers1,771

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Decline zyxin and CALLY index as predictors of cardiovascular diseases in patients with T2DM.Wiad Lek202642359857PubTator, text miningPubMed
Sweetening the bonds: how O-GlcNAcylation modulates cell adhesion.Acta Pharmacol Sin202642332029PubTator, text miningPubMed
Magnetic torque-mediated early asymmetric mechanical stimulation directs structural and functional maturation in human cardiac organoids.Sci Rep202642115257PubTator, text miningPubMed
Reconstituted nascent adhesion condensates drive actin polymerization on supported lipid bilayers.Sci Adv202642102206PubTator, text miningPubMed
Myosin forces remodel F-actin for mechanosensitive protein recognition.Nature202642020745PubTator, text miningPubMed
Distinct Proteomic Signatures Driving Progression of Sarcopenia: A Longitudinal Multicohort Study.J Cachexia Sarcopenia Muscle202641782349PubTator, text miningPubMed
Lactylation-based machine algorithm combined with multi-omics analysis to predict prognosis in cervical cancer.Oncol Lett202641743011PubTator, text miningPubMed
The Potential Link and Role of Zyxin in the Pathogenesis of Psoriasis and Its Associated Comorbidities.Int J Mol Sci202641596291PubTator, text miningPubMed
Persistent immune, coagulation and cardiac dysregulation are correlated with later post-discharge mortality in children with severe malnutrition.BMC Med202641572258PubTator, text miningPubMed
Focal Adhesion and Cancer Cell Cycle-Associated Resistance.ACS Omega202641552449PubTator, text miningPubMed

1 to 10 of 1,771

See all 1,771 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7791

GET https://conductscience.org/api/genes/v1/7791/patents?page=2