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DDR1: discoidin domain receptor tyrosine kinase 1
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Gene · 780

Papers2,465

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,465

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TitleJournalYearPMIDFound bySource
Epigenome-Wide Association Study of Abdominal Aortic Aneurysm Identifies Central Role for Inflammatory Pathways.Circulation202642808173PubTator, text miningPubMed
Anlotinib enhances the sensitivity to docetaxel in lung cancer through inhibiting DDR1-mediated glycolytic pathway.Int J Biol Sci202642807855PubTator, text miningPubMed
DDR1 sustains ferroptosis resistance in pancreatic ductal adenocarcinoma via SLC40A1-mediated iron homeostasis.Oncogene202642778663PubTator, text miningPubMed
Inflammatory memory inactivates AMPK-stimulated DDR1 degradation to enable pancreatic cancer growth.Proc Natl Acad Sci U S A202642771502PubTator, text miningPubMed
Supermeres Containing the Discoidin Domain Receptor 1 Extracellular Domain Promote Collagen Alignment and Immune Exclusion in Microsatellite-Stable Colorectal Cancer.Cancer Res Commun202642673563PubTator, text miningPubMed
Type I collagen matrix signaling in cancer: receptor sensing and mechanotransduction.Cell Signal202642660397PubTator, text miningPubMed
Beyond Physical Proximity and "Tool Cells": The Missing Catalytic Evidence in the DDR1-STAT3 Axis of Keloids.Br J Dermatol202642640734PubTator, text miningPubMed
Reply to 'Beyond physical proximity and "tool cells": the missing catalytic evidence in the DDR1-STAT3 axis of keloids'.Br J Dermatol202642631507PubTator, text miningPubMed
HSP27 regulates force-coordinated DDR1 condensate disassembly and liquid-to-gel phase transition.Sci Adv202642599996PubTator, text miningPubMed
Integrating genomic structural equation modeling and experimental validation to unravel the genetic basis of male genital lichen sclerosus.Front Immunol202642553536PubTator, text miningPubMed
Discovery of pyrazole derivative IHMT-140 as a pancreatic cancer therapeutic agent via dual mechanisms DDR1 inhibition and methuosis induction.J Adv Res202642521155PubTator, text miningPubMed
Transcriptomic Profiling of the Effects of DDR1 in Breast and Ovarian Cancer to Understand the Association Between DDR1 Expression and Patient Survival.Genes (Basel)202642510800PubTator, text miningPubMed
RAG-GNN: retrieval-augmented graph neural networks for protein interaction network embeddings.Front Artif Intell202642499761PubTator, text miningPubMed
An Overview of Emerging Trends in Targeted Therapy of Triple-Negative Breast Cancer.Int J Breast Cancer202642488779PubTator, text miningPubMed
Multiomics integrative bioinformatics analysis of gene expression characteristics and molecular mechanisms in preeclampsia placental tissue.Artif Cells Nanomed Biotechnol202642473750PubTator, text miningPubMed
Discoidin domain receptor 1 contributes to colorectal cancer progression by promoting cell migration and invasion.Life Sci202642462480PubTator, text miningPubMed
Single nucleus RNA profiling reveals potential therapeutic vulnerabilities in sinonasal carcinomas.NPJ Precis Oncol202642414478PubTator, text miningPubMed
Quantification of Binding of Small Molecules to Native Kinases by Flow Cytometry Reveals Divergence from Biochemical Affinities.J Am Chem Soc202642336767PubTator, text miningPubMed
Hypoxia and lactate metabolism-related gene COL5A3 promotes triple negative breast cancer progression via DDR1/FAK/PI3K/AKT pathway.Biol Direct202642310796PubTator, text miningPubMed
Extracellular matrix stiffness determines the phenotypic behavior of dedifferentiated melanoma cells through a DDR1/2-dependent YAP mechanotransduction pathway.Oncogenesis202642288492PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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