Gene · 7827
NPHS2: NPHS2 stomatin family member, podocin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NPHS2: NPHS2 stomatin family member, podocin. Genes, record 7827. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7827
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NP85 | Podocin | 383 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55198 | Q9NP85 | Espacenet |
| WO 2025253101 A1 | 2025-12-11 | 11 | Q9NP85 | Espacenet |
| JP 2025539119 A | 2025-12-03 | 10 | Q9NP85 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8447 | Q9NP85 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2879 | Q9NP85 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2879 | Q9NP85 | Espacenet |
| KR 1020250112259 A | 2025-07-23 | 10 | Q9NP85 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8447 | Q9NP85 | Espacenet |
| WO 2025003703 A1 | 2025-01-02 | 29 | Q9NP85 | Espacenet |
| WO 2025003709 A1 | 2025-01-02 | 7 | Q9NP85 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,051
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NPHS2 papers | Newest fiscal year |
|---|---|---|---|
| R01DK076077 | Adaptive and maladaptive repair after kidney injury | 8 | 2025 |
| R01DK104753 | Crosstalk Between Lipid Droplets and Other Organelles in Podocytes | 6 | 2025 |
| I01BX004024 | Transport and metabolism in the kidney | 5 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30DK020579 | Diabetes Research Center | 4 | 2025 |
| P30DK036836 | Diabetes Research Center | 4 | 2025 |
| K23DK125529 | Defining the molecular landscape of hyperfiltration-mediated glomerular injury using kidney allografts as a model system | 3 | 2025 |
| P20GM121334 | Mississippi Center of Excellence in Perinatal Research, Phase 2 | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,051Source NIH's project files
See all 1,051 nih grantsPapers2,376
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Network pharmacology, single-cell transcriptomics, machine learning and experimental validation identifying CHEK2 and HPGD as key therapeutic targets of berberine in diabetic nephropathy. | Funct Integr Genomics | 2026 | 42821141 | PubTator, text mining | PubMed |
| Functional characterization of genetic variants associated with rare inherited renal disorders in the Sri Lankan population. | Mol Genet Genomics | 2026 | 42814169 | PubTator, text mining | PubMed |
| Promoter Hypermethylation-Driven NPHS2 Silencing Promotes Immune Escape and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma. | Oncol Res | 2026 | 42769428 | PubTator, text mining | PubMed |
| Kidney organoids as a platform to study plasminogen-induced injury and uPA-based therapies. | Stem Cells Transl Med | 2026 | 42768826 | PubTator, text mining | PubMed |
| A novel redox signalling axis mediates nicotine-induced podocyte injury. | Front Pharmacol | 2026 | 42661778 | PubTator, text mining | PubMed |
| Podocin oligomerization links slit-diaphragm architecture and NPHS2 genetics. | Kidney Int | 2026 | 42612985 | PubTator, text mining | PubMed |
| Anti-podocin and Anti-KIRREL1 Antibodies and Steroid Resistance, FSGS, and Disease Recurrence after Transplantation in Autoimmune Podocytopathies. | J Am Soc Nephrol | 2026 | 42490149 | PubTator, text mining | PubMed |
| LncRNA GATA3-AS1-mediated miR-2116-5p interaction modulates TCF12 and contributes to podocyte dysfunction in childhood nephrotic syndrome. | Clinics (Sao Paulo) | 2026 | 42462511 | PubTator, text mining | PubMed |
| Ubiquitination-Related Diagnostic Biomarkers for Diabetic Nephropathy: Insights From Multiomic Analysis, Drug Docking, and Experimental Validation. | FASEB J | 2026 | 42461218 | PubTator, text mining | PubMed |
| Selective JNK3 Inhibition Ameliorates TGF- β -Mediated Glomerular Injury and Fibrosis in the Kidneys. | J Am Soc Nephrol | 2026 | 42440378 | PubTator, text mining | PubMed |
1 to 10 of 2,376
See all 2,376 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7827
GET https://conductscience.org/api/genes/v1/7827/patents?page=2