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Gene · 7827

NPHS2: NPHS2 stomatin family member, podocin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NPHS2: NPHS2 stomatin family member, podocin. Genes, record 7827. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7827

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Gene

Symbol
NPHS2
HGNC
Name
NPHS2 stomatin family member, podocin
HGNC
NCBI Gene ID
7827
NCBI Gene
HGNC ID
HGNC:13394
HGNC
Ensembl
ENSG00000116218
NCBI Gene
Aliases
PDCN, SRN1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NP85Podocin3830Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455198Q9NP85Espacenet
WO 2025253101 A12025-12-1111Q9NP85Espacenet
JP 2025539119 A2025-12-0310Q9NP85Espacenet
EP 4641201 A22025-10-298447Q9NP85Espacenet
JP 2025529142 A2025-09-042879Q9NP85Espacenet
US 12371689 B22025-07-292879Q9NP85Espacenet
KR 1020250112259 A2025-07-2310Q9NP85Espacenet
JP 2025517969 A2025-06-128447Q9NP85Espacenet
WO 2025003703 A12025-01-0229Q9NP85Espacenet
WO 2025003709 A12025-01-027Q9NP85Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,051

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNPHS2 papersNewest fiscal year
R01DK076077Adaptive and maladaptive repair after kidney injury82025
R01DK104753Crosstalk Between Lipid Droplets and Other Organelles in Podocytes62025
I01BX004024Transport and metabolism in the kidney52025
P30DK020572Michigan Diabetes Research Center (MDRC)52025
P30CA016672Cancer Center Support Grant42025
P30DK020579Diabetes Research Center42025
P30DK036836Diabetes Research Center42025
K23DK125529Defining the molecular landscape of hyperfiltration-mediated glomerular injury using kidney allografts as a model system32025
P20GM121334Mississippi Center of Excellence in Perinatal Research, Phase 232025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025

1 to 10 of 1,051Source NIH's project files

See all 1,051 nih grants

Papers2,376

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Network pharmacology, single-cell transcriptomics, machine learning and experimental validation identifying CHEK2 and HPGD as key therapeutic targets of berberine in diabetic nephropathy.Funct Integr Genomics202642821141PubTator, text miningPubMed
Functional characterization of genetic variants associated with rare inherited renal disorders in the Sri Lankan population.Mol Genet Genomics202642814169PubTator, text miningPubMed
Promoter Hypermethylation-Driven NPHS2 Silencing Promotes Immune Escape and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma.Oncol Res202642769428PubTator, text miningPubMed
Kidney organoids as a platform to study plasminogen-induced injury and uPA-based therapies.Stem Cells Transl Med202642768826PubTator, text miningPubMed
A novel redox signalling axis mediates nicotine-induced podocyte injury.Front Pharmacol202642661778PubTator, text miningPubMed
Podocin oligomerization links slit-diaphragm architecture and NPHS2 genetics.Kidney Int202642612985PubTator, text miningPubMed
Anti-podocin and Anti-KIRREL1 Antibodies and Steroid Resistance, FSGS, and Disease Recurrence after Transplantation in Autoimmune Podocytopathies.J Am Soc Nephrol202642490149PubTator, text miningPubMed
LncRNA GATA3-AS1-mediated miR-2116-5p interaction modulates TCF12 and contributes to podocyte dysfunction in childhood nephrotic syndrome.Clinics (Sao Paulo)202642462511PubTator, text miningPubMed
Ubiquitination-Related Diagnostic Biomarkers for Diabetic Nephropathy: Insights From Multiomic Analysis, Drug Docking, and Experimental Validation.FASEB J202642461218PubTator, text miningPubMed
Selective JNK3 Inhibition Ameliorates TGF- β -Mediated Glomerular Injury and Fibrosis in the Kidneys.J Am Soc Nephrol202642440378PubTator, text miningPubMed

1 to 10 of 2,376

See all 2,376 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7827

GET https://conductscience.org/api/genes/v1/7827/patents?page=2