Gene · 7850
IL1R2: interleukin 1 receptor type 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IL1R2: interleukin 1 receptor type 2. Genes, record 7850. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7850
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P27930 | Interleukin-1 receptor type 2 | 398 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents173
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705273 A2 | 2026-03-11 | 296 | P27930 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50136 | P27930 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50137 | P27930 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 206 | P27930 | Espacenet |
| JP 2025172069 A | 2025-11-20 | 207 | P27930 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5879 | P27930 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6966 | P27930 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6967 | P27930 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16686 | P27930 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2084 | P27930 | Espacenet |
1 to 10 of 173
See all 173 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,026
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IL1R2 papers | Newest fiscal year |
|---|---|---|---|
| R01AI015614 | Pathogenesis of Fever in Man | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 5 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 5 | 2025 |
| P01AI039671 | Costimulatory Mechanisms of Autoimmunity | 4 | 2025 |
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 4 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 4 | 2025 |
| R01HL076246 | Chemokines in healing myocardial infarction | 4 | 2025 |
| R01HL085440 | Resolution of inflammation in healing myocardial infarcts | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
1 to 10 of 2,026Source NIH's project files
See all 2,026 nih grantsPapers2,718
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| IL-1R2+ neutrophils define an early sterile injury-expanded subset that restrains inflammation and promotes repair. | JCI Insight | 2026 | 42771477 | PubTator, text mining | PubMed |
| Targeted proteomics reveal histiocytosis-associated neurodegeneration signatures. | Hemasphere | 2026 | 42707979 | PubTator, text mining | PubMed |
| A Decoy-Receptor-Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration. | Adv Sci (Weinh) | 2026 | 42621674 | PubTator, text mining | PubMed |
| Integrated Bioinformatics Analysis Identifies FCER1G, IL1R2, and BST1 as Diagnostic Biomarkers and Therapeutic Targets in Sepsis. | J Clin Lab Anal | 2026 | 42590911 | PubTator, text mining | PubMed |
| IL1R2⁺ Inflammatory Monocytes Contribute to Immune Dysregulation and Predict Mortality in COVID-19. | Shock | 2026 | 42580331 | PubTator, text mining | PubMed |
| Machine learning identifies neutrophil-related signatures for diagnostic value in neonatal sepsis. | J Clin Biochem Nutr | 2026 | 42524644 | PubTator, text mining | PubMed |
| Circulating immune profiling reveals impaired monocyte states and trajectories driving immunosuppression in glioblastoma. | J Neuroinflammation | 2026 | 42464264 | PubTator, text mining | PubMed |
| Systems-level insights into bronchopulmonary dysplasia from meta-analysis of genome-scale studies. | Respir Res | 2026 | 42458458 | PubTator, text mining | PubMed |
| IL1R2 identified as a key hub gene regulating vascular endothelial function in Kawasaki disease. | Sci Rep | 2026 | 42373790 | PubTator, text mining | PubMed |
| Blood transcriptomic endotyping of COPD identifies a neutrophil-driven inflammatory endotype reflected by the neutrophil-to-lymphocyte ratio. | Respir Res | 2026 | 42351125 | PubTator, text mining | PubMed |
1 to 10 of 2,718
See all 2,718 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7850
GET https://conductscience.org/api/genes/v1/7850/patents?page=2