Gene · 7855
FZD5: frizzled class receptor 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FZD5: frizzled class receptor 5. Genes, record 7855. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7855
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13467 | Frizzled-5 | 585 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents60
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026183201 A1 | 2026-09-03 | 5 | Q13467 | Espacenet |
| WO 2026183314 A1 | 2026-09-03 | 5 | Q13467 | Espacenet |
| JP 2026120541 A | 2026-07-22 | 65 | Q13467 | Espacenet |
| JP 2026082857 A | 2026-05-19 | 65 | Q13467 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7901 | Q13467 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1642 | Q13467 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1642 | Q13467 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7901 | Q13467 | Espacenet |
| JP 2023532431 A | 2023-07-28 | 82 | Q13467 | Espacenet |
| JP 2023517010 A | 2023-04-21 | 80 | Q13467 | Espacenet |
1 to 10 of 60
See all 60 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| VANTICTUMAB | CHEMBL2364652 | Frizzled-5 antagonist | ANTAGONIST |
Source ChEMBL
Trials3
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT02005315 | VANTICTUMAB | PHASE1 | ClinicalTrials.gov | |
| NCT01973309 | VANTICTUMAB | PHASE1 | ClinicalTrials.gov | |
| NCT01957007 | VANTICTUMAB | PHASE1 | ClinicalTrials.gov |
NIH grants1,489
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FZD5 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 6 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 5 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 5 | 2025 |
| T32AI007526 | Emerging and Tropical Infectious Diseases | 5 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 4 | 2025 |
| R01NS080833 | Biology and Engineering of Botulinum Neurotoxins. | 4 | 2025 |
1 to 10 of 1,489Source NIH's project files
See all 1,489 nih grantsPapers1,967
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Propofol-Induced Metabolic, Apoptotic, and Wnt-Frizzled-Related Transcript Changes in MIA PaCa-2 Cells: In Vitro and Bioinformatic Analyses. | Curr Issues Mol Biol | 2026 | 42793306 | PubTator, text mining | PubMed |
| β-carotene alleviates PM2.5-induced pulmonary fibrosis via suppression of the Frizzled5-mediated Wnt5a/Ca2+pathway. | Ecotoxicol Environ Saf | 2026 | 42759460 | PubTator, text mining | PubMed |
| RNF research trends and an RNF43-based prognostic model for colorectal cancer with immune microenvironment analysis. | Discov Oncol | 2026 | 42671492 | PubTator, text mining | PubMed |
| FZD5 drives macrophage-mediated immunomodulation and predicts prognosis in glioma: evidence from single-cell sequencing. | BMC Cancer | 2026 | 42410370 | PubTator, text mining | PubMed |
| Controlling Tricyclic Peptide Architecture in mRNA Display through Orthogonal Reactivity on Rotationally Flexible Scaffolds. | ACS Chem Biol | 2026 | 42205060 | PubTator, text mining | PubMed |
| Integrative analysis identifies DCBLD2 and immune-related biomarkers for major depressive disorder: evidence from human peripheral blood, post-mortem brain, and rat models. | Front Hum Neurosci | 2026 | 42148317 | PubTator, text mining | PubMed |
| Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation. | J Biomed Mater Res B Appl Biomater | 2026 | 42032797 | PubTator, text mining | PubMed |
| Antimicrobial peptide LL37 ameliorated experimental inflammation induced neonatal lung injury through macrophage immunomodulation. | Pediatr Neonatol | 2026 | 41935947 | PubTator, text mining | PubMed |
| Single-cell insights into trophoblast heterogeneity and adaptive dysfunction in selective fetal growth restriction. | Commun Biol | 2026 | 41845016 | PubTator, text mining | PubMed |
| Frizzled-9 Expression Is Associated With Aggressive Clinicopathological Features and Reduced Overall Survival in Invasive Breast Carcinoma. | Pathol Int | 2026 | 41808318 | PubTator, text mining | PubMed |
1 to 10 of 1,967
See all 1,967 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7855
GET https://conductscience.org/api/genes/v1/7855/patents?page=2