Gene · 7879
RAB7A: RAB7A, member RAS oncogene family
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RAB7A: RAB7A, member RAS oncogene family. Genes, record 7879. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7879
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51149 | Ras-related protein Rab-7a | 207 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4759327 A2 | 2026-06-17 | 43 | P51149 | Espacenet |
| US 12648964 B2 | 2026-06-09 | 19 | P51149 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2430 | P51149 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2430 | P51149 | Espacenet |
| US 12291557 B2 | 2025-05-06 | 55 | P51149 | Espacenet |
| JP 2025020284 A | 2025-02-12 | 122 | P51149 | Espacenet |
| JP 2024529474 A | 2024-08-06 | 43 | P51149 | Espacenet |
| JP 2024509530 A | 2024-03-04 | 33 | P51149 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 698 | P51149 | Espacenet |
| US 11865184 B2 | 2024-01-09 | 42 | P51149 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,674
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RAB7A papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| U19AI135972 | SARS-CoV adaptations through a Systems Biology Lens (SYBIL) | 6 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 5 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 5 | 2025 |
| U19AI135990 | HPMI: Host Pathogen Mapping Initiative | 5 | 2025 |
| P01AI063302 | The intersection of innate and adaptive immunity to intracellular pathogens | 4 | 2025 |
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 4 | 2025 |
| P30DA018343 | Yale/NIDA Neuroproteomics Center | 4 | 2025 |
| R01DK048370 | Small GTP Binding Proteins in Gastrointestinal Mucosa | 4 | 2025 |
1 to 10 of 1,674Source NIH's project files
See all 1,674 nih grantsPapers2,139
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Interrogation of functional variants in COPD GWAS loci by massively parallel reporter assays. | Am J Respir Cell Mol Biol | 2026 | 42745457 | PubTator, text mining | PubMed |
| Mitochondrial Fis1 tunes Rab7A activity via TBC1D15 modulating STING degradation. | Cell Rep | 2026 | 42715104 | PubTator, text mining | PubMed |
| Comparative proteomic and metabolomic profiling of transparent versus opaque pigeon egg albumen. | J Sci Food Agric | 2026 | 42706888 | PubTator, text mining | PubMed |
| Endolysosomal iron-associated vesicular changes and ferroptosis-related vulnerability in VPS13A-knockdown cells. | Mol Biol Rep | 2026 | 42663743 | PubTator, text mining | PubMed |
| Expression of Concern: Knockdown of Rab7a suppresses the proliferation, migration and xenograft tumor growth of breast cancer cells. | Biosci Rep | 2026 | 42565210 | PubTator, text mining | PubMed |
| Nanoparticle-Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple-Negative Breast Cancer by Modulating RAB7A Ubiquitination-Associated Stability and Autophagy. | Adv Sci (Weinh) | 2026 | 42559728 | PubTator, text mining | PubMed |
| Non-canonical role of Ku80 stabilizes Rab7A to enhance mitolysosome formation and chemotherapy in liver cancer. | Commun Biol | 2026 | 42399387 | PubTator, text mining | PubMed |
| Frontotemporal dementia associated CHCHD10V57E mutation aggravates tau pathology via disrupting the CHCHD10-Rab7A-TBC1D15 complex. | Cell Death Dis | 2026 | 42321182 | PubTator, text mining | PubMed |
| Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus. | Analyst | 2026 | 42312723 | PubTator, text mining | PubMed |
| Cell size-dependent mRNA transcription drives proteome remodeling. | Cell Rep | 2026 | 42275220 | PubTator, text mining | PubMed |
1 to 10 of 2,139
See all 2,139 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7879
GET https://conductscience.org/api/genes/v1/7879/patents?page=2