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Gene · 7879

RAB7A: RAB7A, member RAS oncogene family

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RAB7A: RAB7A, member RAS oncogene family. Genes, record 7879. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7879

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Gene

Symbol
RAB7A
HGNC
Name
RAB7A, member RAS oncogene family
HGNC
NCBI Gene ID
7879
NCBI Gene
HGNC ID
HGNC:9788
HGNC
Ensembl
ENSG00000075785
NCBI Gene
Aliases
CMT2B, PRO2706, RAB7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51149Ras-related protein Rab-7a20710Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4759327 A22026-06-1743P51149Espacenet
US 12648964 B22026-06-0919P51149Espacenet
EP 4650780 A22025-11-192430P51149Espacenet
JP 2025517970 A2025-06-122430P51149Espacenet
US 12291557 B22025-05-0655P51149Espacenet
JP 2025020284 A2025-02-12122P51149Espacenet
JP 2024529474 A2024-08-0643P51149Espacenet
JP 2024509530 A2024-03-0433P51149Espacenet
US 11884978 B22024-01-30698P51149Espacenet
US 11865184 B22024-01-0942P51149Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,674

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRAB7A papersNewest fiscal year
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System82025
P30CA008748Cancer Center Support Grant62025
U19AI135972SARS-CoV adaptations through a Systems Biology Lens (SYBIL)62025
P30CA016087Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
U19AI135990HPMI: Host Pathogen Mapping Initiative52025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens42025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.42025
P30DA018343Yale/NIDA Neuroproteomics Center42025
R01DK048370Small GTP Binding Proteins in Gastrointestinal Mucosa42025

1 to 10 of 1,674Source NIH's project files

See all 1,674 nih grants

Papers2,139

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Interrogation of functional variants in COPD GWAS loci by massively parallel reporter assays.Am J Respir Cell Mol Biol202642745457PubTator, text miningPubMed
Mitochondrial Fis1 tunes Rab7A activity via TBC1D15 modulating STING degradation.Cell Rep202642715104PubTator, text miningPubMed
Comparative proteomic and metabolomic profiling of transparent versus opaque pigeon egg albumen.J Sci Food Agric202642706888PubTator, text miningPubMed
Endolysosomal iron-associated vesicular changes and ferroptosis-related vulnerability in VPS13A-knockdown cells.Mol Biol Rep202642663743PubTator, text miningPubMed
Expression of Concern: Knockdown of Rab7a suppresses the proliferation, migration and xenograft tumor growth of breast cancer cells.Biosci Rep202642565210PubTator, text miningPubMed
Nanoparticle-Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple-Negative Breast Cancer by Modulating RAB7A Ubiquitination-Associated Stability and Autophagy.Adv Sci (Weinh)202642559728PubTator, text miningPubMed
Non-canonical role of Ku80 stabilizes Rab7A to enhance mitolysosome formation and chemotherapy in liver cancer.Commun Biol202642399387PubTator, text miningPubMed
Frontotemporal dementia associated CHCHD10V57E mutation aggravates tau pathology via disrupting the CHCHD10-Rab7A-TBC1D15 complex.Cell Death Dis202642321182PubTator, text miningPubMed
Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus.Analyst202642312723PubTator, text miningPubMed
Cell size-dependent mRNA transcription drives proteome remodeling.Cell Rep202642275220PubTator, text miningPubMed

1 to 10 of 2,139

See all 2,139 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7879

GET https://conductscience.org/api/genes/v1/7879/patents?page=2