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Gene · 79109

MAPKAP1: MAPK associated protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MAPKAP1: MAPK associated protein 1. Genes, record 79109. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79109

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Gene

Symbol
MAPKAP1
HGNC
Name
MAPK associated protein 1
HGNC
NCBI Gene ID
79109
NCBI Gene
HGNC ID
HGNC:18752
HGNC
Ensembl
ENSG00000119487
NCBI Gene
Aliases
JC310, MGC2745, MIP1, SIN1, SIN1b, SIN1g
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BPZ7Target of rapamycin complex 2 subunit MAPKAP152223Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192538Q9BPZ7Espacenet
JP 2025517970 A2025-06-122538Q9BPZ7Espacenet
US 11446398 B22022-09-2052448Q9BPZ7Espacenet
US 11446398 B22022-09-2052451Q9BPZ7Espacenet
JP 2022524081 A2022-04-27155419Q9BPZ7Espacenet
JP 2022524081 A2022-04-27155422Q9BPZ7Espacenet
US 11078247 B22021-08-036581Q9BPZ7Espacenet
JP 2017121240 A2017-07-1351918Q9BPZ7Espacenet
JP 2017121240 A2017-07-1351922Q9BPZ7Espacenet
JP 2015518704 A2015-07-0651918Q9BPZ7Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,838

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMAPKAP1 papersNewest fiscal year
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes182025
P30CA016672Cancer Center Support Grant152025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center152025
P30CA008748Cancer Center Support Grant102025
I01CX000916Signaling Pathways and Therapeutic Targeting of Leukemic Cells82025
P30CA006973Regional Oncology Research Center52025
R01DK056695SGK Regulation of Epithelial Sodium Transport52025
P30CA014520UW Comprehensive Cancer Center Support42025
P30CA054174Mays Cancer Center at UT Health SA42025
P30DK020593Vanderbilt Diabetes Research Center42025

1 to 10 of 1,838Source NIH's project files

See all 1,838 nih grants

Papers2,634

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Molecular and structural basis for replication initiation and strand separation by human mitochondrial DNA polymerase γ.Nucleic Acids Res202642788360PubTator, text miningPubMed
Remineralization of Artificial Caries-like Lesions in Permanent Enamel by MI Paste One: Comparative Physicochemical Outcomes and In Vitro Resistance to Secondary Demineralization.J Funct Biomater202642506559PubTator, text miningPubMed
The role of mTORC2 in the in vitro neurotoxicity of Parkinsonian mimetics 6-OHDA and MPP.Neurotoxicology202642320558PubTator, text miningPubMed
GLUT3 drives paclitaxel resistance in peritoneal metastatic gastric cancer by promoting H3K18 lactylation-mediated MAPKAP1 transcription to suppress ferroptosis.Int J Biol Sci202642157923PubTator, text miningPubMed
Uremic Toxins and the Lung Alveolar Capillary Barrier: A Narrative Review.Toxins (Basel)202641893549PubTator, text miningPubMed
Structural and mechanistic basis of mTORC2 activation of protein kinase AKT/PKB.Biochem J202641774454PubTator, text miningPubMed
Comprehensive Review of Antiphospholipid Syndrome: Over Four Decades of Advances and Challenges.Cells202641744799PubTator, text miningPubMed
Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 axis disrupts metabolic-epigenetic crosstalk and suppresses progression in hyperglycolytic breast cancer.Cancer Lett202641707978PubTator, text miningPubMed
Involvement of Non-Muscle Myosin Light Chain Kinase Nitration in Molecular Regulation of Inflammation-Induced Endothelial Cell Barrier Dysfunction.Cells202641677625PubTator, text miningPubMed
The mTORC2 component SIN1 post-transcriptionally regulates TYMS levels and modulates P53 activity in response to 5-FU chemotherapy.Cell Commun Signal202641606600PubTator, text miningPubMed

1 to 10 of 2,634

See all 2,634 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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