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Gene · 7913

DEK: DEK proto-oncogene

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. DEK: DEK proto-oncogene. Genes, record 7913. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7913

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Gene

Symbol
DEK
HGNC
Name
DEK proto-oncogene
HGNC
NCBI Gene ID
7913
NCBI Gene
HGNC ID
HGNC:2768
HGNC
Ensembl
ENSG00000124795
NCBI Gene
Aliases
D6S231E
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P35659Protein DEK3756Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443532P35659Espacenet
EP 4650780 A22025-11-1919700P35659Espacenet
JP 2025517970 A2025-06-1219700P35659Espacenet
US 11446398 B22022-09-2023631P35659Espacenet
JP 2022524081 A2022-04-27126602P35659Espacenet
US 10845365 B22020-11-243P35659Espacenet
US 10449202 B22019-10-2214P35659Espacenet
JP 2019054813 A2019-04-11223967P35659Espacenet
US 9746473 B22017-08-293P35659Espacenet
JP 2017121241 A2017-07-13223967P35659Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,044

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDEK papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
P30CA021765Cancer Center Support Grant (CCSG)132025
P30CA016672Cancer Center Support Grant112025
P30CA016058Cancer Center Support Grant62025
R01DE017336Epigenetic Regulation of Epstein-Barr Virus62025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease52025
R01CA117830Epigenomic Control of KSHV Latency52025
I01BX000803Ron Receptor Tyrosine Kinase Signaling in Breast Cancer42025
P30CA010815Consolidated Basic Cancer Research Program42025
R01GM070503Molecular Recognition During Pre-mRNA Splicing42025

1 to 10 of 1,044Source NIH's project files

See all 1,044 nih grants

Papers1,526

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
RETRACTION: Long Noncoding RNA NR2F1-AS1 Enhances the Migration and Invasion of Hepatocellular Carcinoma via Modulating miR-642a/DEK Pathway.J Oncol202642763456PubTator, text miningPubMed
DEK::AFF2 Fusion-Associated Sinonasal Carcinoma With Intracranial and Orbital Involvement.Case Rep Pathol202642746494PubTator, text miningPubMed
A neuron-distributed DEK integrates ac4C modification and neuroinflammation in pathogenesis of Parkinson disease: evidence from Mendelian randomization, multi-omics and in vitro validation.Front Neurosci202642745872PubTator, text miningPubMed
Scrape Cytology of DEK::AFF2 Fusion-Associated Papillary Squamous Cell Carcinoma of the Sinonasal Tract Masquerading as Schneiderian Papilloma: A Case Report.Acta Cytol202642607006PubTator, text miningPubMed
Differential pro-tumorigenic effects of Helicobacter pylori and Streptococcus anginosus on AGS cells: contact-dependent versus metabolite-driven mechanisms.mBio202642535843PubTator, text miningPubMed
DEK loss in HeLa cells does not alter genotoxic stress sensitivity and DNA damage response.MicroPubl Biol202642428301PubTator, text miningPubMed
DEK recruits KAT6A regulate H3K27ac/c-myc axis to drive enhanced glycolysis and immune escape in gastric cancer.Free Radic Biol Med202642419650PubTator, text miningPubMed
Phosphorylated DEK sustains leukemia stem cells by enabling PBX3-driven transcriptional reprogramming.Blood202642378254PubTator, text miningPubMed
Prostate Cancer: Etiology, Diagnosis, and Treatment.Serican J Med202642375929PubTator, text miningPubMed
Transcriptomic profiling of epigenetic regulators and metabolic reprogramming in human cholangiocarcinoma.Front Cell Dev Biol202642326014PubTator, text miningPubMed

1 to 10 of 1,526

See all 1,526 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7913

GET https://conductscience.org/api/genes/v1/7913/patents?page=2