Gene · 7913
DEK: DEK proto-oncogene
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DEK: DEK proto-oncogene. Genes, record 7913. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7913
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35659 | Protein DEK | 375 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 43532 | P35659 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19700 | P35659 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19700 | P35659 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 23631 | P35659 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 126602 | P35659 | Espacenet |
| US 10845365 B2 | 2020-11-24 | 3 | P35659 | Espacenet |
| US 10449202 B2 | 2019-10-22 | 14 | P35659 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 223967 | P35659 | Espacenet |
| US 9746473 B2 | 2017-08-29 | 3 | P35659 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 223967 | P35659 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,044
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DEK papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 15 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 6 | 2025 |
| R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 6 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 5 | 2025 |
| R01CA117830 | Epigenomic Control of KSHV Latency | 5 | 2025 |
| I01BX000803 | Ron Receptor Tyrosine Kinase Signaling in Breast Cancer | 4 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 4 | 2025 |
| R01GM070503 | Molecular Recognition During Pre-mRNA Splicing | 4 | 2025 |
1 to 10 of 1,044Source NIH's project files
See all 1,044 nih grantsPapers1,526
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| RETRACTION: Long Noncoding RNA NR2F1-AS1 Enhances the Migration and Invasion of Hepatocellular Carcinoma via Modulating miR-642a/DEK Pathway. | J Oncol | 2026 | 42763456 | PubTator, text mining | PubMed |
| DEK::AFF2 Fusion-Associated Sinonasal Carcinoma With Intracranial and Orbital Involvement. | Case Rep Pathol | 2026 | 42746494 | PubTator, text mining | PubMed |
| A neuron-distributed DEK integrates ac4C modification and neuroinflammation in pathogenesis of Parkinson disease: evidence from Mendelian randomization, multi-omics and in vitro validation. | Front Neurosci | 2026 | 42745872 | PubTator, text mining | PubMed |
| Scrape Cytology of DEK::AFF2 Fusion-Associated Papillary Squamous Cell Carcinoma of the Sinonasal Tract Masquerading as Schneiderian Papilloma: A Case Report. | Acta Cytol | 2026 | 42607006 | PubTator, text mining | PubMed |
| Differential pro-tumorigenic effects of Helicobacter pylori and Streptococcus anginosus on AGS cells: contact-dependent versus metabolite-driven mechanisms. | mBio | 2026 | 42535843 | PubTator, text mining | PubMed |
| DEK loss in HeLa cells does not alter genotoxic stress sensitivity and DNA damage response. | MicroPubl Biol | 2026 | 42428301 | PubTator, text mining | PubMed |
| DEK recruits KAT6A regulate H3K27ac/c-myc axis to drive enhanced glycolysis and immune escape in gastric cancer. | Free Radic Biol Med | 2026 | 42419650 | PubTator, text mining | PubMed |
| Phosphorylated DEK sustains leukemia stem cells by enabling PBX3-driven transcriptional reprogramming. | Blood | 2026 | 42378254 | PubTator, text mining | PubMed |
| Prostate Cancer: Etiology, Diagnosis, and Treatment. | Serican J Med | 2026 | 42375929 | PubTator, text mining | PubMed |
| Transcriptomic profiling of epigenetic regulators and metabolic reprogramming in human cholangiocarcinoma. | Front Cell Dev Biol | 2026 | 42326014 | PubTator, text mining | PubMed |
1 to 10 of 1,526
See all 1,526 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7913
GET https://conductscience.org/api/genes/v1/7913/patents?page=2