Gene · 79132
DHX58: DExH-box helicase 58
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DHX58: DExH-box helicase 58. Genes, record 79132. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79132
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96C10 | ATP-dependent RNA helicase DHX58 | 678 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 43679 | Q96C10 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 155 | Q96C10 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 979 | Q96C10 | Espacenet |
| JP 2025138811 A | 2025-09-25 | 100 | Q96C10 | Espacenet |
| JP 2025120300 A | 2025-08-15 | 100 | Q96C10 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 155 | Q96C10 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 979 | Q96C10 | Espacenet |
| US 12123003 B2 | 2024-10-22 | 100 | Q96C10 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 490 | Q96C10 | Espacenet |
| JP 2024501084 A | 2024-01-10 | 245 | Q96C10 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,328
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DHX58 papers | Newest fiscal year |
|---|---|---|---|
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 18 | 2025 |
| P01CA019014 | Viral Oncogenesis, Latency, and Replication | 11 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 11 | 2025 |
| U19AI057266 | Vaccine and Infection Induced Immunity in the Young and Aged | 11 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 10 | 2025 |
| P51OD010425 | Washington National Primate Research Center | 9 | 2025 |
| U19AI089992 | Immune signatures of vaccine responses in vulnerable populations | 9 | 2025 |
| R37AI087846 | Regulation of Host Innate Immunity Against Viral Infection | 7 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 6 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 6 | 2025 |
1 to 10 of 2,328Source NIH's project files
See all 2,328 nih grantsPapers3,877
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The response mechanism of mandarin fish (Siniperca chuatsi) astrocyte-like cells to SCRV infection: Insights from Transcriptome Sequencing. | Fish Shellfish Immunol | 2026 | 42815866 | PubTator, text mining | PubMed |
| MAVS maintains mitochondrial import competence and also limits RNA virus replication independently of interferon signaling. | mBio | 2026 | 42808786 | PubTator, text mining | PubMed |
| Advances in Cytosolic dsRNA Sensing of Viral Infections. | Immunol Cell Biol | 2026 | 42802076 | PubTator, text mining | PubMed |
| Unraveling the Multifaceted Role of TRIM21 in Virus-Triggered Innate Immunity and Diseases. | Biomolecules | 2026 | 42793068 | PubTator, text mining | PubMed |
| Correction: Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5. | Front Immunol | 2026 | 42787502 | PubTator, text mining | PubMed |
| Extended IL-4 priming of macrophages induces an antiviral state that restricts lymphocytic choriomeningitis virus replication. | Cytokine | 2026 | 42777316 | PubTator, text mining | PubMed |
| Elevated ISG15 reinforces RIG-I/MDA5-linked macrophage-microglia crosstalk during blood-brain barrier disruption in neuromyelitis optica spectrum disorder. | Int Immunopharmacol | 2026 | 42763248 | PubTator, text mining | PubMed |
| Carriage of the Laboratory of Genetics and Physiology Protein 2 Q425R Variant Reduces Liver Disease Severity in European Patients With Chronic Hepatitis Delta. | Aliment Pharmacol Ther | 2026 | 42753128 | PubTator, text mining | PubMed |
| Autogenous vaccination protects Pacific oysters against OsHV-1 by reshaping the transcriptome. | Fish Shellfish Immunol | 2026 | 42722176 | PubTator, text mining | PubMed |
| Post-translational control of MAVS signaling: linking mitochondrial antiviral immunity to metabolic and cellular stress contexts. | Front Physiol | 2026 | 42719470 | PubTator, text mining | PubMed |
1 to 10 of 3,877
See all 3,877 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/79132
GET https://conductscience.org/api/genes/v1/79132/patents?page=2