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Gene · 79188

TMEM43: transmembrane protein 43

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TMEM43: transmembrane protein 43. Genes, record 79188. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79188

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Gene

Symbol
TMEM43
HGNC
Name
transmembrane protein 43
HGNC
NCBI Gene ID
79188
NCBI Gene
HGNC ID
HGNC:28472
HGNC
Ensembl
ENSG00000170876
NCBI Gene
Aliases
ARVC5, ARVD5, AUNA3, DKFZp586G1919, EDMD7, EDMD7; AUNA2, LUMA, MGC3222
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BTV4Transmembrane protein 434000Ensembl, GeneID, HGNC

Source UniProt

Patents139

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467845Q9BTV4Espacenet
EP 4650780 A22025-11-194247Q9BTV4Espacenet
JP 2025529142 A2025-09-044909Q9BTV4Espacenet
US 12371689 B22025-07-294909Q9BTV4Espacenet
JP 2025517970 A2025-06-124247Q9BTV4Espacenet
EP 4493703 A22025-01-2214Q9BTV4Espacenet
US 11446398 B22022-09-2091755Q9BTV4Espacenet
US 11400116 B22022-08-025026Q9BTV4Espacenet
JP 2022524081 A2022-04-27194726Q9BTV4Espacenet
US 11078247 B22021-08-0311728Q9BTV4Espacenet

1 to 10 of 139

See all 139 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,122

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTMEM43 papersNewest fiscal year
P50CA058223SPORE in Breast Cancer302025
P30CA016672Cancer Center Support Grant192025
P30CA016086Cancer Center Support Grant152025
P30CA008748Cancer Center Support Grant142025
P30ES010126UNC Center for Environmental Health and Susceptibility82025
R01CA148761Therapeutic Targeting of Breast Cancer Tumor Initiating Cells82025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant62025
P30CA047904Cancer Center Support Grant52025
P30CA012197Cancer Center Support Grant42025
P30CA016087Cancer Center Support Grant42025

1 to 10 of 1,122Source NIH's project files

See all 1,122 nih grants

Papers1,602

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of a nuclear transcriptional module associated with ERα and E2F/FOXM1 signaling across PAM50 breast cancer subtypes.Front Oncol202642620280PubTator, text miningPubMed
Gene Therapy for Cardiovascular and Cerebrovascular Disease: Mechanisms, Translational Barriers, and the Road Ahead.Biomedicines202642193469PubTator, text miningPubMed
Explainable machine learning-guided integrated multiomics analysis reveals macrophage-driven immune suppression in breast cancer.Nat Commun202642185288PubTator, text miningPubMed
Spatial transcriptional mapping reveals the molecular characteristics of juxtaglomerular cell tumors.Front Oncol202642038360PubTator, text miningPubMed
Newfoundland Mutation TMEM43-p.S358L Causes Impaired Cardiac Energy Metabolism and Mitochondrial Function Through Altered Protein Interaction.Circ Genom Precis Med202641919408PubTator, text miningPubMed
Characterization, immune cell phenotyping and differential gene expression analysis of brain metastases and primary breast cancer samples.Sci Rep202641905976PubTator, text miningPubMed
CXCL12-mediated T cell infiltration drives breast cancer metastasis.Clin Exp Med202641902967PubTator, text miningPubMed
An explainable-AI framework reveals novel lncRNAs specific for breast cancer subtypes.Front Bioinform202641884707PubTator, text miningPubMed
Over-the-Counter Loperamide Overdose Resulting in Cardiac Arrest.JACC Case Rep202641854325PubTator, text miningPubMed
An integrative analysis reveals the mechanism of plastic stabilizers inducing breast cancer.PLoS Comput Biol202641790613PubTator, text miningPubMed

1 to 10 of 1,602

See all 1,602 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/79188

GET https://conductscience.org/api/genes/v1/79188/patents?page=2