Gene · 79400
NOX5: NADPH oxidase 5
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NOX5: NADPH oxidase 5. Genes, record 79400. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79400
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q96PH1 | NADPH oxidase 5 | 765 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents11
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55020 | Q96PH1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11023 | Q96PH1 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2869 | Q96PH1 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2869 | Q96PH1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11023 | Q96PH1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 55310 | Q96PH1 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 5035 | Q96PH1 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 158281 | Q96PH1 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 235455 | Q96PH1 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 235455 | Q96PH1 | Espacenet |
1 to 10 of 11
See all 11 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants968
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NOX5 papers | Newest fiscal year |
|---|---|---|---|
| ZIABC010677 | NADPH Oxidases as Novel Targets for Cancer Therapy | 9 | 2025 |
| ZIAAI000947 | Mosquito Immune Responses and Malaria Transmission | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 5 | 2025 |
| R01HL125926 | Galectin-3: A mediator of vascular remodeling in pulmonary arterial hypertension | 5 | 2025 |
| P30AG013319 | San Antonio Nathan Shock Center of Excellence in the Biology of Aging | 4 | 2025 |
| P50AA011999 | Southern California Research Center for ALPD and Cirrhosis | 3 | 2025 |
| R01EY015130 | Mechanisms of Angiogenesis in ROP | 3 | 2025 |
| R01EY017011 | Endothelial Transmigration in Neovascular Age-related Macular Degeneration | 3 | 2025 |
| R01GM102187 | Chemical Tools for Probing Cysteine Sulfenation and Sulfination Redox Biology | 3 | 2025 |
1 to 10 of 968Source NIH's project files
See all 968 nih grantsPapers1,709
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| An Early Value Assessment of Biomarker-Guided Precision Medicine for Treatment-Resistant Hypertension: A Headroom and Threshold Analysis. | Appl Health Econ Health Policy | 2026 | 42814264 | PubTator, text mining | PubMed |
| F-actin-dependent activation of NADPH oxidase 5 by the vacuolar-type ATPase. | J Biol Chem | 2026 | 42727851 | PubTator, text mining | PubMed |
| Dietary Chlorogenic Acid Attenuates Liver Injury, Lipid Metabolic Disturbance, and Inflammatory Responses in Broilers Under High Stocking Density. | Animals (Basel) | 2026 | 42651958 | PubTator, text mining | PubMed |
| Development of a first-in-class homolog-selective, covalent NOX4 inhibitor. | Biomed Pharmacother | 2026 | 42600360 | PubTator, text mining | PubMed |
| Disrupting Redox Balance: A Redox-Based Strategy to Combat Temozolomide Resistance in Glioblastoma. | Anticancer Agents Med Chem | 2026 | 42337877 | PubTator, text mining | PubMed |
| Structural bioinformatic studies of eight integral transmembrane NADPH oxidases and their AlphaFold 3 predicted QTY analogs with reduced hydrophobicity. | PLoS One | 2026 | 42268815 | PubTator, text mining | PubMed |
| Molecular Advances in Male Infertility and Fertility: Importance of Redox Regulation and Oxidative Stress. | Int J Mol Sci | 2026 | 42123404 | PubTator, text mining | PubMed |
| Drugst.One DREAM-Drug repurposing through expert annotation and modification. | Br J Pharmacol | 2026 | 42108670 | PubTator, text mining | PubMed |
WITHDRAWN: Corrigendum to "NADPH oxidase 5 promotes adhesion and infiltration of immune cells in the brain. Implications in ischemic stroke" [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. (2026) volume 1872, issue 4, 168188]. | Biochim Biophys Acta Mol Basis Dis | 2026 | 42020255 | PubTator, text mining | PubMed |
| Single-Cell sequencing investigation of endoplasmic reticulum stress-related genes in gastric cancer prognostic models and identification of NOX5 as a novel therapeutic target. | Transl Oncol | 2026 | 42013548 | PubTator, text mining | PubMed |
1 to 10 of 1,709
See all 1,709 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/79400
GET https://conductscience.org/api/genes/v1/79400/patents