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Gene · 7941

PLA2G7: phospholipase A2 group VII

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. PLA2G7: phospholipase A2 group VII. Genes, record 7941. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/7941

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
PLA2G7
HGNC
Name
phospholipase A2 group VII
HGNC
NCBI Gene ID
7941
NCBI Gene
HGNC ID
HGNC:9040
HGNC
Ensembl
ENSG00000146070
NCBI Gene
Aliases
LDL-PLA2, LP-PLA2, Lp-PLA2, PAFAD, PAFAH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13093Platelet-activating factor acetylhydrolase44133Ensembl, GeneID, HGNC

Source UniProt

Patents110

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457884Q13093Espacenet
JP 2026004568 A2026-01-1457885Q13093Espacenet
US 12509501 B22025-12-3032Q13093Espacenet
EP 4641201 A22025-10-292483Q13093Espacenet
JP 2025147176 A2025-10-0610474Q13093Espacenet
JP 2025147176 A2025-10-0610475Q13093Espacenet
JP 2025529142 A2025-09-047369Q13093Espacenet
US 12371689 B22025-07-297369Q13093Espacenet
JP 2025517969 A2025-06-122483Q13093Espacenet
JP 2025032204 A2025-03-1133546Q13093Espacenet

1 to 10 of 110

See all 110 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DARAPLADIBCHEMBL204021LDL-associated phospholipase A2 inhibitorINHIBITORChEMBL
RILAPLADIBCHEMBL2104981LDL-associated phospholipase A2 inhibitorINHIBITORChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02058641DARAPLADIBPHASE1ClinicalTrials.gov
NCT01916720DARAPLADIBPHASE2ClinicalTrials.gov
NCT01745458RILAPLADIBPHASE1ClinicalTrials.gov
NCT01636271DARAPLADIBClinicalTrials.gov
NCT01506895DARAPLADIBPHASE2ClinicalTrials.gov
NCT01428453RILAPLADIBPHASE22018-09-24ClinicalTrials.gov
NCT00734032DARAPLADIBPHASE22018-01-12ClinicalTrials.gov
NCT00695305RILAPLADIBPHASE2ClinicalTrials.gov
NCT00269048DARAPLADIBPHASE2ClinicalTrials.gov
NCT00268996DARAPLADIBPHASE22018-02-19ClinicalTrials.gov

NIH grants2,346

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)212025
P30DK017047Diabetes Research Center112025
UM1AI068634Statistical and Data Management Center (SDMC), Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG)112025
UM1AI069494Pitt-Ohio State Clinical Trials Unit112025
P30AI036219Rustbelt Center for AIDS Research (Case/UHC-Pitt CFAR)102025
UM1AI068636Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections92025
P30CA016672Cancer Center Support Grant72025
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL72025
P30CA042014Cancer Center Support Grant62025
R01NS017950Precursors of Stroke Incidence and Prognosis62025

1 to 10 of 2,346Source NIH's project files

See all 2,346 nih grants

Papers4,339

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42788303PubTator, text miningPubMed
42737680PubTator, text miningPubMed
42699750PubTator, text miningPubMed
42698451PubTator, text miningPubMed
42665188PubTator, text miningPubMed
42645923PubTator, text miningPubMed
42614551PubTator, text miningPubMed
42580670PubTator, text miningPubMed
42570806PubTator, text miningPubMed
42553033PubTator, text miningPubMed

1 to 10 of 4,339

See all 4,339 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7941

GET https://conductscience.org/api/genes/v1/7941/patents?page=2