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Gene · 79447

PAGR1: PAXIP1 associated glutamate rich protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PAGR1: PAXIP1 associated glutamate rich protein 1. Genes, record 79447. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79447

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Gene

Symbol
PAGR1
HGNC
Name
PAXIP1 associated glutamate rich protein 1
HGNC
NCBI Gene ID
79447
NCBI Gene
HGNC ID
HGNC:28707
HGNC
Ensembl
ENSG00000280789
NCBI Gene
Aliases
C16orf53, GAS, MGC4606, PA1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BTK6PAXIP1-associated glutamate-rich protein 12540Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441429Q9BTK6Espacenet
JP 2025032204 A2025-03-1132845Q9BTK6Espacenet
EP 4461818 A22024-11-1332845Q9BTK6Espacenet
JP 2023058610 A2023-04-2532845Q9BTK6Espacenet
US 11446398 B22022-09-2061523Q9BTK6Espacenet
JP 2022524081 A2022-04-27164494Q9BTK6Espacenet
US 11078247 B22021-08-038087Q9BTK6Espacenet
JP 2020508652 A2020-03-2632845Q9BTK6Espacenet
JP 2019054813 A2019-04-11221864Q9BTK6Espacenet
JP 2017121241 A2017-07-13221864Q9BTK6Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,030

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePAGR1 papersNewest fiscal year
ZIADK075003Enhancer regulation by H3K4 methyltransferase KMT2D/MLL4 and associated factors92025
ZIADK075017Epigenomic regulation of adipogenesis and obesity-associated adipose expansion72025
P30CA008748Cancer Center Support Grant62025
R01DK073368Mechanisms of Compartmentalized cAMP Signaling62025
P30CA016672Cancer Center Support Grant52025
R01DA012864Mechanisms and Cellular Function of Opioid Receptor Endocytosis52025
R35CA197622Live-cell Activity Architecture in Cancer52025
ZIADA000493Functional and Pharmacological Significance of Receptor Heteromers in the CNS52025
ZIADK031117Development of Drugs Acting at Adenosine Receptors52025
P30CA016087Cancer Center Support Grant42025

1 to 10 of 2,030Source NIH's project files

See all 2,030 nih grants

Papers2,678

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multi-omics integration reveals tissue-specific biosynthesis of sesquiterpenoids in the medicinal plant Eupatorium lindleyanum.PLoS One202642821537PubTator, text miningPubMed
Heterotrimeric G proteins containing Gβ1γ2 subunits exhibit subtype-specific mobility differences in live cells.PLoS One202642809568PubTator, text miningPubMed
Calcitonin gene-related peptide promotes mast cell-mediated neuroimmune inflammation through the CALCRL/RAMP1-JAK3-STAT1 axis in rosacea.Front Immunol202642751103PubTator, text miningPubMed
Long non-coding RNA-gm33782 exacerbates acute kidney injury by upregulating the PA1-MLL3/MLL4 complex and promoting histone H3 lysine 4 monomethylation-dependent forkhead box O3 enhancer activation.Int J Biol Macromol202642727675PubTator, text miningPubMed
Spatial control of parathyroid hormone receptor-1 signaling dictates ligand-specific biological outcomes.Signal Transduct Target Ther202642722652PubTator, text miningPubMed
From Structure to Dynamics: Activation Mechanism of the G Protein-Coupled Bile Acid Receptor 1‑Gs Complex.ACS Omega202642662721PubTator, text miningPubMed
Therapeutic targeting of G protein-coupled receptors in central nervous system disorders: from novel mechanisms to precision pharmacology.Eur J Pharmacol202642624449PubTator, text miningPubMed
Finding functional gaps: integrative analysis of VPAC1- and VPAC2-mediated signalling pathways in human lymphocytes.Cell Biosci202642471749PubTator, text miningPubMed
Kinome-wide CRISPR/Cas9-knockout screening reveals critical protein kinases in vasopressin V2-receptor signaling.bioRxiv202642465376PubTator, text miningPubMed
Rudolf Buchheim Award 2026: Regulation of thyroid hormone gatekeepers by thyrotropin in tanycytes.Naunyn Schmiedebergs Arch Pharmacol202642414693PubTator, text miningPubMed

1 to 10 of 2,678

See all 2,678 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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