ConductScience.org, home

Gene · 79661

NEIL1: nei like DNA glycosylase 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. NEIL1: nei like DNA glycosylase 1. Genes, record 79661. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/79661

On this page

Gene

Symbol
NEIL1
HGNC
Name
nei like DNA glycosylase 1
HGNC
NCBI Gene ID
79661
NCBI Gene
HGNC ID
HGNC:18448
HGNC
Ensembl
ENSG00000140398
NCBI Gene
Aliases
FLJ22402, FPG1, NEI1, hFPG1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96FI4Endonuclease 8-like 139027Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2024123008 A2024-09-107277Q96FI4Espacenet
JP 2024123008 A2024-09-107278Q96FI4Espacenet
US 11504404 B22022-11-22153Q96FI4Espacenet
US 11446398 B22022-09-2055828Q96FI4Espacenet
US 11446398 B22022-09-2055831Q96FI4Espacenet
US 11446398 B22022-09-2055839Q96FI4Espacenet
JP 2022524081 A2022-04-27158799Q96FI4Espacenet
JP 2022524081 A2022-04-27158802Q96FI4Espacenet
JP 2022524081 A2022-04-27158810Q96FI4Espacenet
JP 2021169490 A2021-10-28239Q96FI4Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants918

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNEIL1 papersNewest fiscal year
P01CA092584Structural Cell Biology of DNA Repair Machines492025
ZIAAG000723ALZHEIMERS RESEARCH PROJECT: DNA repair dysfunction in neurodegeneration and Alzheimer's Disease122025
P30ES006694Southwest Environmental Health Sciences Center82025
R35CA220430Mesoscale and Nanoscale Technologies Integrated by Structures for DNA Repair Complexes (MANTIS-DRC)82025
P30CA068485Cancer Center Support Grant72025
ZIAAG000726Function of RecQ helicases in genome stability62025
P30CA047904Cancer Center Support Grant52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA042014Cancer Center Support Grant42025
P30CA077598Cancer Center Support Grant42025

1 to 10 of 918Source NIH's project files

See all 918 nih grants

Papers1,435

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Collaborations with Miral Dizdaroglu: expanding on connections between oxidative DNA damage and aging and disease.Int J Radiat Biol202642573227PubTator, text miningPubMed
Base excision repair hierarchy in eukaryotes: Intrinsically disordered region-mediated regulation of genomic surveillance and assembly dynamics.Curr Opin Struct Biol202642127749PubTator, text miningPubMed
A metal ion-dependent mechanism promoting gain of function in NEIL1 variants.Int J Radiat Biol202641974029PubTator, text miningPubMed
Kynurenine Pathway, Nrf2 and NF-κB Cross-Regulation in the CNS: An Overview.Mol Neurobiol202641894093PubTator, text miningPubMed
EEPD1 evolved a unique DNA clamping dimer protecting reversed replication forks.Nucleic Acids Res202641830330PubTator, text miningPubMed
Meeting abstracts from the Annual Conference "Clinical Genetics of Cancer 2024".Hered Cancer Clin Pract202641781972PubTator, text miningPubMed
Detection of germline variants in human population chronically exposed to high level natural background radiation in Kerala coast.Genes Environ202641761368PubTator, text miningPubMed
OGG1 and MUTYH DNA Glycosylases, the Dynamic Duo Against 8-Oxoguanine DNA Lesion: Structure, Regulation, and Novel Emerging Roles.Biomolecules202641750327PubTator, text miningPubMed
Ferroptosis and Alzheimer's disease: a new insight into neurodegeneration.Front Immunol202641727439PubTator, text miningPubMed
Current Insights and Future Directions of Multiomic and Spatial-Omic Analysis in Non-Small Cell Lung Cancer.JCO Precis Oncol202641712875PubTator, text miningPubMed

1 to 10 of 1,435

See all 1,435 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/79661

GET https://conductscience.org/api/genes/v1/79661/patents?page=2